Evaluation of the effects of serum iron levels on lacrimal gland secretion

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dc.authorid0000-0002-6299-7067
dc.authorid0000-0002-2563-2149
dc.authorid0000-0001-9829-7268
dc.contributor.authorErdo?an, Fırat
dc.contributor.authorEliaçık, Mustafa
dc.contributor.authorŞenkal, Evrim
dc.contributor.authorKaraman Erdur, Sevil
dc.contributor.authorKulak, Kudret
dc.contributor.authorÖzahi İpek, İlke
dc.date.accessioned10.07.201910:49:13
dc.date.accessioned2019-07-10T20:01:35Z
dc.date.available10.07.201910:49:13
dc.date.available2019-07-10T20:01:35Z
dc.date.issued2015
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Çocuk Sağlığı ve Hastalıkları Ana Bilim Dalı
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Göz Hastalıkları Ana Bilim Dalı
dc.descriptionWOS: 000358741400006
dc.descriptionPubMed ID: 26228282
dc.description.abstractIn our study we aimed to demonstrate the relationship between the serum iron levels, and tears quality and quantity in term newborns. This study was conducted at a single institution between March 2013 and May 2013. A total of 46 newborns were prospectively enrolled. Serum iron levels were measured via the umbilical cord blood. Infants were divided into two groups according to their serum iron levels. Group A, serum iron level <= 70 mg/dL (n = 27) and Group B, serum iron level >70 mg/dL (n = 19). The evaluation of the osmolarity was tested by using the TearLab Osmolarity System (TearLab Co, San Diego, CA, USA). The assessment of quantity was performed by using Schirmer I test. Osmolarity testing and Schirmer I test (with/without anesthesia) were performed bilaterally on the 1st day of life by an ophthalmologist. The outcomes of Schirmer I and tear osmolarity showed no statistically significant difference between right and left eyes of any infant in the groups. Moreover, there was no statistical difference between sexes in these two groups. Osmolarity was found to have a moderate negative correlation coefficient with serum iron level (r = -0.4, p < 0.01). Furthermore, there was a high positive correlation between Schirmer I with anesthesia and serum iron levels (r = 0.7, p < 0.01). We observed that the quality and quantity of the tears was lower in term newborns with lower serum iron levels than healthy newborns. These results indicate that low serum iron level could affect lacrimal gland functions.
dc.identifier.citationErdo?an, F., Eliaçık, M., Şenkal, E., Karaman Erdur, S., Kulak, K. ve Özahi İpek, İ. (2015). Evaluation of the effects of serum iron levels on lacrimal gland secretion. Kaohsiung Journal of Medical Sciences, 31(8), 426-431. https://dx.doi.org/10.1016/j.kjms.2015.06.003
dc.identifier.doi10.1016/j.kjms.2015.06.003
dc.identifier.endpage431
dc.identifier.issn1607-551X
dc.identifier.issue8
dc.identifier.scopusqualityQ2
dc.identifier.startpage426
dc.identifier.urihttps://dx.doi.org/10.1016/j.kjms.2015.06.003
dc.identifier.urihttps://hdl.handle.net/20.500.12511/3352
dc.identifier.volume31
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherElsevier
dc.relation.ispartofKaohsiung Journal of Medical Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectLacrimalGland
dc.subjectSchirmer Test
dc.subjectSerum Iron Level
dc.subjectTear Osmolarity
dc.subjectTerm Newborn
dc.titleEvaluation of the effects of serum iron levels on lacrimal gland secretion
dc.typeArticle

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