Efficacy and safety of intracorneal allogenic ring segment implantation in keratoconus: 1-year results

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dc.authorid0000-0003-1749-8119
dc.authorid0000-0002-6327-7440
dc.authorid0000-0003-2445-6339
dc.authorid0009-0004-6063-9305
dc.contributor.authorAşık Nacaroğlu, Şenay
dc.contributor.authorYeşilkaya, Elif Ceren
dc.contributor.authorKeskin Perk, Fatma Feyza Nur
dc.contributor.authorTanrıverdi, Cafer
dc.contributor.authorTaneri, Suphi
dc.contributor.authorKılıç, Aylin
dc.date.accessioned2024-01-18T08:19:49Z
dc.date.available2024-01-18T08:19:49Z
dc.date.issued2023
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Göz Hastalıkları Ana Bilim Dalı
dc.description.abstractBackgroundTo evaluate the safety and efficacy of corneal allogenic intrastromal ring segments in the management of keratoconus patients.MethodsThe retrospective, nonrandomized, interventional case series consisted of 65 keratoconic eyes of 49 consecutive patients who had ring segment-shaped corneal allografts (KeraNatural (R)) implanted in intrastromal tunnels created using a femtosecond laser. The main outcome measures were uncorrected visual acuity (UCVA), corrected distant visual acuity (CDVA), refraction, keratometry, and pachymetry. Computed tomography scans of the corneal surfaces were also performed preoperatively as well as 3, 6 and 12 months postoperatively.ResultsMean age was 29.5 +/- 7.3 years (median 29, range: 20-52 years). The mean UCVA improved from 0.91 +/- 0.50 logMAR preoperatively to 0.40 +/- 0.24 logMAR postoperatively at 6 month follow-up (p < 0.01) and the mean CDVA improved from 0.87 +/- 0.20 logMAR preoperatively to 0.27 +/- 0.06 logMAR postoperatively (p < 0.01). The mean spherical equivalent improved from -8.82 +/- 4.57 to -3.45 +/- 4.81D (p < 0.01). Average Keratometry decreased from 49.23 +/- 5.22 preoperatively to 45.63 +/- 4.89 D postoperatively (p < 0.01). Mean anterior and posterior maximum elevation were also decreased significantly (p < 0.01). In one patient, dislocation of the graft towards the tunnel incision site and dehiscense at the tunnel entrance were observed in the first week of the operation. Yellow-white deposits were observed in the segment tunnels in five cases after 6 months.ConclusionThis study demonstrated that implantation of corneal allograft ring segments is a viable alternative treatment for keratoconus with safety and good visual results.
dc.identifier.citationAşık Nacaroğlu, Ş., Yeşilkaya, E. C., Keskin Perk, F. F. N., Tanrıverdi, C., Taneri, S. ve Kılıç, A. (2023). Efficacy and safety of intracorneal allogenic ring segment implantation in keratoconus: 1-year results. Eye (Basingstoke), 37(18), 3807-3812. https://dx.doi.org/10.1038/s41433-023-02618-5
dc.identifier.doi10.1038/s41433-023-02618-5
dc.identifier.endpage3812
dc.identifier.issn0950-222X
dc.identifier.issn1476-5454
dc.identifier.issue18
dc.identifier.pmid37328510
dc.identifier.scopus2-s2.0-85162015117
dc.identifier.scopusqualityN/A
dc.identifier.startpage3807
dc.identifier.urihttps://dx.doi.org/10.1038/s41433-023-02618-5
dc.identifier.urihttps://hdl.handle.net/20.500.12511/12166
dc.identifier.volume37
dc.identifier.wos001009157300002en_US
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorAşık Nacaroğlu, Şenay
dc.institutionauthorKeskin Perk, Fatma Feyza Nur
dc.institutionauthorTanrıverdi, Cafer
dc.institutionauthorKılıç, Aylin
dc.language.isoen
dc.publisherSpringer Nature
dc.relation.ispartofEye (Basingstoke)en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectIntracorneal Allogenic
dc.subjectSegment Implantation
dc.titleEfficacy and safety of intracorneal allogenic ring segment implantation in keratoconus: 1-year results
dc.typeArticle

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