Pea3 transcription factor promotes neurite outgrowth

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dc.authorid0000-0002-5072-132X
dc.contributor.authorKandemir, Başak
dc.contributor.authorÇağlayan, Berrak
dc.contributor.authorHausott, Barbara
dc.contributor.authorErdoğan, Burcu
dc.contributor.authorDağ, Uğur
dc.contributor.authorDemir, Özlem
dc.contributor.authorSavaşan Soğut, Melis
dc.contributor.authorKlimaschewski, Lars
dc.contributor.authorAksan Kurnaz, Işıl
dc.date.accessioned10.07.201910:49:13
dc.date.accessioned2019-07-10T19:36:33Z
dc.date.available10.07.201910:49:14
dc.date.available2019-07-10T19:36:33Z
dc.date.issued2014
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Fizyoloji Ana Bilim Dalı
dc.description.abstractPea3 subfamily of E-twenty six transcription factors consist of three major -exhibit branching morphogenesis, the function of Pea3 family in nervous system development and regeneration is only beginning to unfold. In this study, we provide evidence that Pea3 can directs neurite extension and axonal outgrowth in different model systems, and that Serine 90 is important for this function. We have also identified neurofilament-L and neurofilament-M as two putative novel targets for Pea3.
dc.description.sponsorshipTurkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK)en_US
dc.description.sponsorshipBrain Research Society BAD-Lundbeck Project Awarden_US
dc.description.sponsorshipTurkish Academy of Scienceen_US
dc.identifier.citationKandemir, B., Çağlayan, B., Hausott, B., Erdoğan, B., Dağ, U., Demir, Ö. ... Aksan Kurnaz, I. (2014). Pea3 transcription factor promotes neurite outgrowth. Frontiers in Molecular Neuroscience, 7, 11-14. https://dx.doi.org/10.3389/fnmol.2014.00059
dc.identifier.doi10.3389/fnmol.2014.00059
dc.identifier.issn1662-5099
dc.identifier.scopusqualityQ2
dc.identifier.urihttps://hdl.handle.net/20.500.12511/1194
dc.identifier.urihttps://dx.doi.org/10.3389/fnmol.2014.00059
dc.identifier.volume7
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherFrontiers Research Foundation
dc.relation.ispartofFrontiers in Molecular Neuroscienceen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.relation.tubitakinfo:eu-repo/grantAgreement/TUBITAK/SOBAG/106S247
dc.relation.tubitakinfo:eu-repo/grantAgreement/TUBITAK/SOBAG/107S284
dc.rightsAttribution 3.0 Unported*
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttps://creativecommons.org/licenses/by/3.0/*
dc.subjectAxonal Outgrowth
dc.subjectNeurofilaments
dc.subjectNeuron
dc.subjectPea3
dc.subjectPhosphorylation
dc.titlePea3 transcription factor promotes neurite outgrowth
dc.typeArticle

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