Is neutrophil-lymphocyte ratio associated with the severity of allergic rhinitis in children?

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dc.authorid0000-0003-0606-864X
dc.contributor.authorDoğru, Mahmut
dc.contributor.authorEvcimik, Muhammed Fatih
dc.contributor.authorCırık, Ahmet Adnan
dc.date.accessioned10.07.201910:49:13
dc.date.accessioned2019-07-10T19:52:17Z
dc.date.available10.07.201910:49:13
dc.date.available2019-07-10T19:52:17Z
dc.date.issued2016
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Kulak Burun Boğaz Hastalıkları Ana Bilim Dalı
dc.descriptionWOS: 000382945900039
dc.descriptionPubMed ID: 26525883
dc.description.abstractNeutrophil lymphocyte ratio (NLR) could be an important measure of systemic inflammation. There is a lack of knowledge about the neutrophil-lymphocyte ratio in rhinitis. We aimed to determine the relationship between the clinical parameters of allergic rhinitis and NLR in children. 438 children who were diagnosed with allergic rhinitis and followed up in our hospital were included in the study. The control group included 180 control children with no evidence of allergic disease. The immunoglobulin E levels, skin prick tests and complete blood count were measured. Mean NLR was 1.77 +/- A 1.67 in the study group and 1.70 +/- A 1.65 in the control group. Mean NLR was significantly higher in children with allergic rhinitis compared to controls (p < 0.05). The patients with allergic rhinitis were grouped according to the severity of AR as Group I (mild group) and Group II (moderate/severe group). No statistically significant difference was present between groups in terms of gender, age, familial atopy, exposure to smoke, the presence of asthma and/or eczema, the percentage of eosinophil, serum IgE levels, number of positive sensitivity, and sensitivity to allergens (p > 0.05). However, NLR was significantly higher in the moderate/severe AR compared to mild AR (p < 0.05). Mean NLR was statistically higher in children with allergic rhinitis compared to the control group. In addition, elevated ratio is associated with the severity of allergic rhinitis in children. Neutrophil-lymphocyte can be used as an indicator of inflammation in allergic rhinitis. But further studies are needed in this issue.
dc.identifier.citationDoğru, M., Evcimik, M. F. ve Cırık, A. A. (2016). Is neutrophil-lymphocyte ratio associated with the severity of allergic rhinitis in children? European Archives of Oto-Rhino-Laryngology, 273(10), 3175-3178. https://dx.doi.org/10.1007/s00405-015-3819-y
dc.identifier.doi10.1007/s00405-015-3819-y
dc.identifier.endpage3178
dc.identifier.issn0937-4477
dc.identifier.issn1434-4726
dc.identifier.issue10
dc.identifier.scopusqualityQ1
dc.identifier.startpage3175
dc.identifier.urihttps://dx.doi.org/10.1007/s00405-015-3819-y
dc.identifier.urihttps://hdl.handle.net/20.500.12511/2376
dc.identifier.volume273
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherSpringer
dc.relation.ispartofEuropean Archives of Oto-Rhino-Laryngologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectNeutrophil-Lymphocyte Ratio
dc.subjectChildren
dc.subjectSeverity
dc.subjectInflammation
dc.subjectAllergic Rhinitis
dc.subjectIndicator
dc.titleIs neutrophil-lymphocyte ratio associated with the severity of allergic rhinitis in children?
dc.typeArticle

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