Prevalence of restless legs syndrome among psychiatric patients who are under antidepressant or antipsychotic monotherapy

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dc.contributor.authorSemiz, Murat
dc.contributor.authorSolmaz, Volkan
dc.contributor.authorAksoy, Dürdane
dc.contributor.authorİnanır, Sema
dc.contributor.authorÇolak, Burçin
dc.contributor.authorGökbakan, Mehmet Aziz
dc.contributor.authorİnanır, Ahmet
dc.date.accessioned10.07.201910:49:13
dc.date.accessioned2019-07-10T20:01:36Z
dc.date.available10.07.201910:49:13
dc.date.available2019-07-10T20:01:36Z
dc.date.issued2016
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Ruh Sağlığı ve Hastalıkları Ana Bilim Dalı
dc.descriptionWOS: 000383390400009
dc.description.abstractObjective: Several groups of medications, such as dopamine blockers, analgesics and antihistaminergics were associated with restless legs syndrome (RLS). Although case reports showed some significant relations, they have many methodological limitations such as co-medications or medical co-morbidities. The aim of this study was to investigate the prevalence and severity of RLS in patients on antidepressant (AD) or antipsychotic (AP) monotherapy. Methods: One hundred and ninety-seven patients and 150 healthy controls were included in the study. RLS was diagnosed according to the International Restless Legs Syndrome Study Group (IRLSSG) criteria. The severity of RLS was evaluated according to IRLSSG rating scale. Participants diagnosed with RLS went under further neurological and psychiatric investigation for excluding secondary causes. Results: One hundred and twenty patients (60.9%) were on AD therapy, while 77 patients (39.1%) were on AP monotherapy. Thirty-two patients (16.2%) and seven controls (4.7%) were diagnosed with RLS according to IRLSSG criteria. The most frequent cause of RLS was quetiapine (28.5%) in the antipsychotic group and paroxetine (22.2%) in the antidepressant group. There was no statistically significant correlation between drug usage duration and RLS severity. Conclusion: AD or AP induced RLS is a common condition. ADs and APs should be considered as a cause for RLS when assesing RLS in psychiatric patients who are under treatment either of these medications.
dc.identifier.citationSemiz, M., Solmaz, V., Aksoy, D., İnanır, S., Çolak, B., Gökbakan, M. A. ... İnanır, A. (2016). Prevalence of restless legs syndrome among psychiatric patients who are under antidepressant or antipsychotic monotherapy. Klinik Psikofarmakoloji Büteni-Bulletin Of Clinical Psychopharmacology, 26(2), 161-168. https://dx.doi.org/10.5455/bcp.20150908024954
dc.identifier.doi10.5455/bcp.20150908024954
dc.identifier.endpage168
dc.identifier.issn1017-7833
dc.identifier.issue2
dc.identifier.scopusqualityN/A
dc.identifier.startpage161
dc.identifier.urihttps://dx.doi.org/10.5455/bcp.20150908024954
dc.identifier.urihttps://hdl.handle.net/20.500.12511/3360
dc.identifier.volume26
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherKüre İletişim Grubu A S
dc.relation.ispartofKlinik Psikofarmakoloji Büteni-Bulletin Of Clinical Psychopharmacologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectAntidepressant
dc.subjectAntipsychotic
dc.subjectRestless Legs Syndrome
dc.subjectAdverse Effect
dc.titlePrevalence of restless legs syndrome among psychiatric patients who are under antidepressant or antipsychotic monotherapy
dc.typeArticle

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