Gamma Knife radiosurgery for the treatment of trigeminal neuralgia: A single center-experience

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dc.contributor.authorAkçakaya, Mehmet Osman
dc.contributor.authorMirkhasilova, Muyassar
dc.contributor.authorÖztürk, Onur
dc.contributor.authorUğurlar, Doğa
dc.contributor.authorTönge, Mehmet
dc.contributor.authorAlço, Gül
dc.contributor.authorErcan, Tülay
dc.contributor.authorİğdem, Şefik
dc.contributor.authorKaradereler, Selhan
dc.date.accessioned2025-03-07T09:45:39Z
dc.date.available2025-03-07T09:45:39Z
dc.date.issued2024
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Beyin ve Sinir Cerrahisi Ana Bilim Dalı
dc.description.abstractIntroduction and objectives: We aimed to assess the outcomes of patients with trigeminal neuralgia (TGN) who underwent Gamma Knife radiosurgery (GKRS). Materials and methods: Fifty-three patients with typical TGN underwent GKRS from May 2012 until December 2022. Among these patients, 45 patients who were follow-up for at least 12 months were included in the study. A mean dose of 87.5 Gy (range, 80–90) was administered to the trigeminal nerve. Postoperatively, outcome was considered excellent if the patient was pain- and medication-free. Results: The mean symtpom duration was 9.53 years, and the mean patient age was 59.8 years (range, 34–85). The mean follow-up period was 46.8 months (range, 12–127 months). 46.7% of patients had a history of previous surgical interventions. A single nerve division was affected in 14 patients (31.1%), and multiple divisions were affected in 31 patients (68.9%). The rate of initial pain relief was 80%. Hypoesthesia in the area of trigeminal nerve developed in 30 (66.7%). Twenty patients (44.4%) exhibited excellent results within 72.4 months. Recurrence occurred in 11 patients (24.4%) with 27.6 months. Conclusions: Our results suggest that GKRS is a safe and effective procedure. Thus, it is an attractive first- and second-line treatment choice for TGN.
dc.identifier.citationAkçakaya, M. O., Mirkhasilova, M., Öztürk, O., Uğurlar, D., Tönge, M., Alço, G. ... Karadereler, S. (2024). Gamma Knife radiosurgery for the treatment of trigeminal neuralgia: A single center-experience. Neurocirugia, 35(5), 225-232. http://dx.doi.org/10.1016/j.neucir.2024.03.003
dc.identifier.doi10.1016/j.neucir.2024.03.003
dc.identifier.endpage232
dc.identifier.issn1130-1473
dc.identifier.issn2340-6305
dc.identifier.issue5
dc.identifier.pmid38642616
dc.identifier.scopus2-s2.0-85202471829
dc.identifier.scopusqualityQ3
dc.identifier.startpage225
dc.identifier.urihttp://dx.doi.org/10.1016/j.neucir.2024.03.003
dc.identifier.urihttps://hdl.handle.net/20.500.12511/12894
dc.identifier.volume35
dc.identifier.wosWOS:001316637200001
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorTönge, Mehmet
dc.institutionauthorid0000-0002-0106-9363
dc.language.isoen
dc.relation.ispartofNeurocirugia
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectGamma Knife
dc.subjectOutcome
dc.subjectRadiosurgery
dc.subjectTrigeminal Neuralgia
dc.titleGamma Knife radiosurgery for the treatment of trigeminal neuralgia: A single center-experience
dc.title.alternativeRadiocirugía Gamma-Knife para el tratamiento de la neuralgia del trigémino: una experiencia en un solo centro
dc.typeArticle

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