Allograft corneal ring segment for keratoconus management: Istanbul nomogram clinical results

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dc.authorid0000-0003-3634-5433
dc.authorid0000-0003-2445-6339
dc.authorid0000-0002-6327-7440
dc.authorid0000-0001-8880-0026
dc.contributor.authorHacıağaoğlu, Sezer
dc.contributor.authorTanrıverdi, Cafer
dc.contributor.authorKeskin, Fatma Feyza Nur
dc.contributor.authorTran, Khoa D.
dc.contributor.authorKılıç, Aylin
dc.date.accessioned2023-09-14T07:02:17Z
dc.date.available2023-09-14T07:02:17Z
dc.date.issued2023
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Göz Hastalıkları Ana Bilim Dalı
dc.description.abstractPurpose To evaluate the clinical feasibility and visual outcomes of allograft corneal ring segment implantation for the treatment of keratoconus. Methods This case series, included forty-four eyes of 32 patients with a 6-month follow-up. All cases were treated according to the Istanbul nomogram. In the Istanbul Nomogram, corneal tunnels of 4 x 7.5 mm diameters are created at depth of 200 mu m and implanted with sterile allograft corneal rings (KeraNaturalTM, Lions VisionGift, Portland, OR, USA) at the cone location. Uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), spherical equivalent (SE) and keratometric values were compared preoperatively versus postoperatively. Results There was significant improvement in UDVA, CDVA, SE and topographic keratometric values. The mean preoperative CDVA (Snellen, decimal) increased from 0.29 +/- 0.20, to 0.56 +/- 0.26 (P < 0.001), at the last visit. There was no statistically significant difference between preoperative and postoperative thinnest pachymetry values (P = 0.509). No major complications or adverse event were observed during and after the operation. Conclusions The results of this pilot study show that sterile allograft corneal ring segments may be safe, effective and enhance the visual performance of keratoconus patients. Larger clinical studies are needed to demonstrate the effectiveness and safety with long term follow-up.
dc.identifier.citationHacıağaoğlu, S., Tanrıverdi, C., Keskin, F. F. N., Tran, K. D. ve Kılıç, A. (2023). Allograft corneal ring segment for keratoconus management: Istanbul nomogram clinical results. European Journal of Ophthalmology, 33(2), 689-696. https://dx.doi.org/10.1177/11206721221142995
dc.identifier.doi10.1177/11206721221142995
dc.identifier.endpage696
dc.identifier.issn1120-6721
dc.identifier.issn1724-6016
dc.identifier.issue2
dc.identifier.pmid36464653
dc.identifier.scopus2-s2.0-85144209998
dc.identifier.scopusqualityQ2
dc.identifier.startpage689
dc.identifier.urihttps://dx.doi.org/10.1177/11206721221142995
dc.identifier.urihttps://hdl.handle.net/20.500.12511/11426
dc.identifier.volume33
dc.identifier.wos000893576700001en_US
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorHacıağaoğlu, Sezer
dc.institutionauthorTanrıverdi, Cafer
dc.institutionauthorKeskin, Fatma Feyza Nur
dc.institutionauthorKılıç, Aylin
dc.language.isoen
dc.publisherSAGE Publications Ltd
dc.relation.ispartofEuropean Journal of Ophthalmologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectAllograft Corneal Ring
dc.subjectCAIRS
dc.subjectIntracorneal Ring Segment
dc.subjectKeranatural
dc.subjectKeratoconus
dc.titleAllograft corneal ring segment for keratoconus management: Istanbul nomogram clinical results
dc.typeArticle

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