Surgery for secondary hyperparathyroidism. Total or subtotal?

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dc.authorid0000-0001-8036-8021
dc.contributor.authorBirsen, Onur
dc.contributor.authorÖzban, Murat
dc.contributor.authorÖzden, Akın
dc.contributor.authorSüngürtekin, Uğur
dc.contributor.authorErdem, Ergün
dc.contributor.authorKabay, Burhan
dc.contributor.authorYılmaz, Sevda
dc.contributor.authorAykota, Muhammed Raşid
dc.contributor.authorÖzgen, Utku
dc.contributor.authorDemirci, Samet
dc.contributor.authorAydın, Hüseyin Çağatay
dc.date.accessioned2023-01-12T10:36:58Z
dc.date.available2023-01-12T10:36:58Z
dc.date.issued2022
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Genel Cerrahi Ana Bilim Dalı
dc.description.abstractObjectives Secondary hyperparathyroidism (sHPT) develops as a result of the chronic parathyroid stimulation associated with hypocalcemia, hyperphosphatemia, or vitamin D deficiency and leads to an increase in parathormone (PTH) synthesis and parathyroid cell proliferation in all of the four glands. Background There are currently three surgical approaches to the treatment of renal hyperparathyroidism: subtotal parathyroidectomy, total parathyroidectomy without autotransplantation, and total parathyroidectomy with autotransplantation. Methods Included in the study were 79 of which 35 underwent a total parathyroidectomy with autotransplantation (TPTX+AT), while 44 patients underwent a subtotal parathyroidectomy (SPTX). Results A significant decrease was noted in PTH, calcium, and phosphate levels following both types of parathyroidectomy. It was observed that PTH and phosphate serum levels were controlled significantly better following a total parathyroidectomy with autotransplantation, and the recurrence rate was higher in the subtotal parathyroidectomy group (14.3% vs. 27.3%). Conclusion Considering its significantly superior outcomes in the short- and long-term, total parathyroidectomy with autotransplantation should be the preferred treatment option in countries where access to kidney transplantation is difficult and where healthcare services are expensive.
dc.identifier.citationBirsen, O., Özban, M., Özden, A., Süngürtekin, U., Erdem, E., Kabay, B. ... Aydın, H. Ç. (2022). Surgery for secondary hyperparathyroidism. Total or subtotal? Indian Journal of Surgery, 84(1), 94-99. https://dx.doi.org/10.1007/s12262-021-02821-2
dc.identifier.doi10.1007/s12262-021-02821-2
dc.identifier.endpage99
dc.identifier.issn0972-2068
dc.identifier.issn0973-9793
dc.identifier.issue1
dc.identifier.scopus2-s2.0-85103371693
dc.identifier.scopusqualityQ4
dc.identifier.startpage94
dc.identifier.urihttps://dx.doi.org/10.1007/s12262-021-02821-2
dc.identifier.urihttps://hdl.handle.net/20.500.12511/10294
dc.identifier.volume84
dc.identifier.wos000635871700001en_US
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.institutionauthorAydın, Hüseyin Çağatay
dc.language.isoen
dc.publisherSpringer India
dc.relation.ispartofIndian Journal of Surgeryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectEnd-Stage Renal Disease
dc.subjectParathyroidectomy
dc.subjectRenal Transplantation
dc.subjectSecondary Hyperparathyroidism
dc.titleSurgery for secondary hyperparathyroidism. Total or subtotal?
dc.typeArticle

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