Predictive value of C-reactive protein/albumin ratio for no-reflow in patients with Non-ST-elevation myocardial infarction

dc.authorid0000-0003-0230-6575
dc.contributor.authorTosu, Aydın Rodi
dc.contributor.authorÇınar, Tufan
dc.contributor.authorKalyoncuo?lu, Muhsin
dc.contributor.authorBiter, Halil İbrahim
dc.contributor.authorÇakal, Sinem
dc.contributor.authorÇakal, Beytullah
dc.contributor.authorSelçuk, Murat
dc.contributor.authorBelen, Erdal
dc.contributor.authorCan, Mehmet Mustafa
dc.date.accessioned2023-03-14T11:36:00Z
dc.date.available2023-03-14T11:36:00Z
dc.date.issued2022
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Kardiyoloji Ana Bilim Dalı
dc.description.abstractIntroduction: The focus of this research was to explore the link between CRP (C-reactive protein)/albumin ratio (CAR), a novel inflammatory response marker, and no-reflow (NR) phenomena in non-ST elevation myocardial infarction (non-STEMI) patients during percutaneous coronary intervention (PCI). Methods: The current study recruited 209 non-STEMI participants who underwent PCI. The patients were divided into two groups based on their post-intervention Thrombolysis in Myocardial Infarction (TIMI) flow grade; those with and without NR. Results: In all, 30 non-STEMI patients (6.9%) had NR after PCI. CAR values were substantially greater in the NR group. The CAR was identified to be a determinant of the NR (OR: 1.250, 95% CI: 1.033-1.513, P = 0.02), although CRP and albumin were not independently related with NR in the multivariate analysis. In our investigation, low density lipoprotein-cholesterol levels and high thrombus burden were also predictors of the occurrence of NR. According to receiver operating characteristic curve evaluation, the optimal value of CAR was > 1.4 with 60% sensitivity and 47% specificity in detecting NR in non-STEMI patients following PCI. Conclusion: To the best of knowledge, this is the first investigation to demonstrate that the CAR, a new and useful inflammatory marker, can be utilized as a predictor of NR in patients with non-STEMI prior to PCI.
dc.identifier.citationTosu, A. R., Çınar, T., Kalyoncuo?lu, M., Biter, H. İ., Çakal, S., Çakal, B. ... Can, M. M. (2022). Predictive value of C-reactive protein/albumin ratio for no-reflow in patients with Non-ST-elevation myocardial infarction. Journal of Cardiovascular and Thoracic Research, 14(4), 214-219. https://dx.doi.org/10.34172/jcvtr.2022.30549
dc.identifier.doi10.34172/jcvtr.2022.30549
dc.identifier.endpage219
dc.identifier.issn2008-5117
dc.identifier.issn2008-6830
dc.identifier.issue4
dc.identifier.pmid36699552
dc.identifier.scopus2-s2.0-85149023493
dc.identifier.scopusqualityQ4
dc.identifier.startpage214
dc.identifier.urihttps://dx.doi.org/10.34172/jcvtr.2022.30549
dc.identifier.urihttps://hdl.handle.net/20.500.12511/10615
dc.identifier.volume14
dc.identifier.wos000890311300001en_US
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorÇakal, Beytullah
dc.language.isoen
dc.publisherTabriz University of Medical Sciences
dc.relation.ispartofJournal of Cardiovascular and Thoracic Researchen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsAttribution 4.0 International*
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/*
dc.subjectC-reactive Protein
dc.subjectCAR
dc.subjectNo-Reflow
dc.subjectSerum Albumin
dc.titlePredictive value of C-reactive protein/albumin ratio for no-reflow in patients with Non-ST-elevation myocardial infarction
dc.typeArticle

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