Association of eosinophil-to-lymphocyte ratio with coronary slow-flow phenomenon in patients undergoing coronary angiography

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dc.authorid0000-0003-0230-6575
dc.contributor.authorTosu, Aydın Rodi
dc.contributor.authorKalyoncuoğlu, Muhsin
dc.contributor.authorBiter, Halil İbrahim
dc.contributor.authorÇakal, Sinem
dc.contributor.authorÇakal, Beytullah
dc.contributor.authorSelçuk, Murat
dc.contributor.authorÇınar, Tufan
dc.date.accessioned2023-02-21T12:29:49Z
dc.date.available2023-02-21T12:29:49Z
dc.date.issued2022
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Kardiyoloji Ana Bilim Dalı
dc.description.abstractIntroduction: The current investigation intended to evaluate the correlation between eosinophil-to-lymphocyte ratio (ELR) and the coronary slow-flow phenomenon (CSFP) in patients undergoing elective coronary angiography. Material and methods: A case-control investigation was conducted on 200 individual CSFP patients and another 200 individuals with normal coronary arteries and who were matched for age, gender, and body mass index. ELR was computed by dividing the number of eosinophils by the number of lymphocytes. Thrombolysis in myocardial infarction frame count was used to determine the CSFP. Results: The ELR in the CSFP group was substantially greater than in the control group [0.38 (0.28-0.50)] and [0.22 (0.17-0.35)], p < 0.001, respectively). With the help of multivariable logistic regression analysis, ELR independently predicted the CSFP presence (odds ratio = 1.040, 95% CI: 1.026-1.053), p < 0.001). The effective cutoff point of ELR in predicting CSFP presence was > 0.29 with sensitivity of 77% and specificity of 70%. ELR had better diagnostic accuracy to predict CSFP than either lymphocyte or eosinophil count alone [AUC = 0.746 vs. AUC = 0.687 vs. AUC = 0.687, respectively]. Conclusions: To our knowledge, this was the first investigation to determine the connection between ELR and CSFP. We discovered that individuals with CSFP had higher ELR than those with normal coronary arteries in the control group.
dc.identifier.citationTosu, A. R., Kalyoncuoğlu, M., Biter, H. İ., Çakal, S., Çakal, B., Selçuk, M. ve Çınar, T. (2022). Association of eosinophil-to-lymphocyte ratio with coronary slow-flow phenomenon in patients undergoing coronary angiography. Archives of Medical Science - Atherosclerotic Diseases, 7, e29-e35. https://doi.org/10.5114/amsad.2022.116662
dc.identifier.doi10.5114/amsad.2022.116662
dc.identifier.endpagee35
dc.identifier.issn2451-0629
dc.identifier.pmid35846412
dc.identifier.startpagee29
dc.identifier.urihttps://doi.org/10.5114/amsad.2022.116662
dc.identifier.urihttps://hdl.handle.net/20.500.12511/10494
dc.identifier.volume7
dc.indekslendigikaynakPubMed
dc.institutionauthorÇakal, Beytullah
dc.language.isoen
dc.publisherTermedia Publishing House
dc.relation.ispartofArchives of Medical Science - Atherosclerotic Diseasesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/embargoedAccess
dc.subjectEosinophils
dc.subjectInflammation
dc.subjectLymphocytes
dc.titleAssociation of eosinophil-to-lymphocyte ratio with coronary slow-flow phenomenon in patients undergoing coronary angiography
dc.typeArticle

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