Is there an association between vitamin B12 level and vitamin D status in children?
| dc.authorid | 0000-0002-8003-1952 | |
| dc.authorid | 0000-0002-0560-1580 | |
| dc.contributor.author | Karabayır, Nalan | |
| dc.contributor.author | Teber, Burcu Gizem | |
| dc.contributor.author | Dursun, Hatice Kübra | |
| dc.contributor.author | Sezen Pehlivan, Lale | |
| dc.date.accessioned | 2022-04-08T06:38:57Z | |
| dc.date.available | 2022-04-08T06:38:57Z | |
| dc.date.issued | 2022 | |
| dc.department | İstanbul Medipol Üniversitesi, Uluslararası Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Çocuk Sağlığı ve Hastalıkları Ana Bilim Dalı | |
| dc.department | İstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Çocuk Sağlığı ve Hastalıkları Ana Bilim Dalı | |
| dc.description.abstract | Vitamin B12 (vit B12) or cobalamin is a water-soluble vitamin that acts as a coenzyme and is effective in the formation of a healthy nervous system and erythrocytes. In its deficiency, except fatigue and weakness, may cause serious signs and symptoms such as macrocytic anemia, cognitive-developmental delay, irreversible neurological damage. In this study, hemoglobin, leukocyte, thrombocyte, iron, iron-binding, ferritin, and vit B12 levels were evaluated retrospectively during the routine controls of 689 children 5 to 18 years old without any complaints. In addition, the relationship between serum 25-Hydroxyvitamin D (vit D) levels and vit B12 levels, which were evaluated in 487 of the cases, was investigated. Vit B12 deficiency was diagnosed in a total of 160 (23.2%) cases, 99 (24.4%) girls and 61 (21.4%) boys. Vit B12 level was significantly lower in children over 12 years old. Vitamin D deficiency was found to be 49.3% in 487 cases and was significantly higher in the group under 12 years and girls. The frequency of anemia was 7.2% in this group. There was a significant relationship between vit D deficiency and vit B12 deficiency. In conclusion, vit B12 deficiency is common in school-age children, especially in the adolescent age group. It should be known that vit D deficiency may also be present in vit B12 deficiency cases. More comprehensive studies are needed to reveal the relationship between B12 and vit D deficiency. | |
| dc.identifier.citation | Karabayır, N., Teber, B. G., Dursun, H. K. ve Sezen Pehlivan, L. (2022). Is there an association between vitamin B12 level and vitamin D status in children? Journal of Pediatric Hematology/Oncology, 44(3), E677-E681. https://doi.org/10.1097/MPH.0000000000002329 | |
| dc.identifier.doi | 10.1097/MPH.0000000000002329 | |
| dc.identifier.endpage | E681 | |
| dc.identifier.issn | 1077-4114 | |
| dc.identifier.issn | 1536-3678 | |
| dc.identifier.issue | 3 | |
| dc.identifier.pmid | 35319507 | |
| dc.identifier.scopus | 2-s2.0-85117860932 | |
| dc.identifier.scopusquality | Q3 | |
| dc.identifier.startpage | E677 | |
| dc.identifier.uri | https://doi.org/10.1097/MPH.0000000000002329 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.12511/9256 | |
| dc.identifier.volume | 44 | |
| dc.identifier.wos | 000772033500022 | en_US |
| dc.identifier.wosquality | Q4 | |
| dc.indekslendigikaynak | Web of Science | |
| dc.indekslendigikaynak | Scopus | |
| dc.indekslendigikaynak | PubMed | |
| dc.institutionauthor | Karabayır, Nalan | |
| dc.institutionauthor | Teber, Burcu Gizem | |
| dc.institutionauthor | Dursun, Hatice Kübra | |
| dc.language.iso | en | |
| dc.publisher | Lippincott Williams and Wilkins | |
| dc.relation.ispartof | Journal of Pediatric Hematology/Oncology | en_US |
| dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | |
| dc.rights | info:eu-repo/semantics/embargoedAccess | |
| dc.subject | Anemia | |
| dc.subject | School Aged Children | |
| dc.subject | Vitamin B12 | |
| dc.subject | Vitamin D | |
| dc.title | Is there an association between vitamin B12 level and vitamin D status in children? | |
| dc.type | Article |
