Geographical variations and predictors of coronary artery disease mortality in Turkiye: an environmental and behavioral analysis

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dc.contributor.authorTutar, Mehmet
dc.contributor.authorKoçak, Hilal Gülendam
dc.contributor.authorKoçak, Mehmet
dc.date.accessioned2025-10-06T13:42:15Z
dc.date.available2025-10-06T13:42:15Z
dc.date.issued2024
dc.departmentİstanbul Medipol Üniversitesi, Uluslararası Tıp Fakültesi
dc.description.abstractObjective: This study aims to analyze the geographical variations and identify key environmental and behavioral predictors of coronary artery disease (CAD) mortality in Turkiye. Methods: A 10-year longitudinal province-level data was used to identify change trajectories of CAD mortality. Environmental determinants (such as air quality and climatic conditions) and behavioral factors of alcohol consumption and smoking were examined for their association with CAD mortality change trajectories using Ordinal Logistic Regression models. Results: The study revealed significantly different trajectoriesof CAD mortality across Turkiye. Environmental factors, particularly air quality (Particulate Matter-10 variation) and climatic conditions (humidity and temperature variations), were heavily associated with the level of CAD mortality. Behavioral factors, notably alcohol consumption and smoking, also exhibited a significantly positive association. Humidity, sunlight, and temperature remained as key predictors of CAD after controlling for smoking and alcohol consumption. Conclusion: The study underscores the importance of addressing environmental and lifestyle factors in CAD management and prevention strategies. The findings suggest the necessity for region-specific interventions and public health policies tailored to the unique characteristics of each province in Turkiye. This research contributes to a deeper understanding of the multifactorial nature of CAD mortality, providing valuable insights for future research to investigate causal associations, healthcare planning, and policy-making. Trial registration: Our study has been registered in ClinicalTrials.GOV system with a procotol ID of CAD001.
dc.description.sponsorshipTUBITAK Directorate of Science Fellowships and Grant Programmes (BIDEB)-2232 International Fellowship for Outstanding Researchers
dc.identifier.citationTutar, M., Koçak, H. G. ve Koçak, M. (2024). Geographical variations and predictors of coronary artery disease mortality in Turkiye: an environmental and behavioral analysis. BMC Cardiovascular Disorders, 24(1). http://dx.doi.org/10.1186/s12872-024-04240-z
dc.identifier.doi10.1186/s12872-024-04240-z
dc.identifier.issn1471-2261
dc.identifier.issue1
dc.identifier.pmid39395979
dc.identifier.scopus2-s2.0-85206123356
dc.identifier.scopusqualityQ2
dc.identifier.urihttp://dx.doi.org/10.1186/s12872-024-04240-z
dc.identifier.urihttps://hdl.handle.net/20.500.12511/13079
dc.identifier.volume24
dc.identifier.wosWOS:001336419300001
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorKoçak, Hilal Gülendam
dc.institutionauthorKoçak, Mehmet
dc.institutionauthorid0009-0009-3621-8654
dc.institutionauthorid0000-0002-3386-1734
dc.language.isoen
dc.relation.ispartofBMC Cardiovascular Disorders
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.relation.tubitakinfo:eu-repo/grantAgreement/TUBITAK/SOBAG/118C306
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 International
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subjectBehavioral Factors
dc.subjectCoronary Artery Disease
dc.subjectEnvironmental Factors
dc.subjectGeographical Variations
dc.subjectMortality
dc.subjectTurkiye
dc.titleGeographical variations and predictors of coronary artery disease mortality in Turkiye: an environmental and behavioral analysis
dc.typeArticle

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