A retrospective analysis of 83 patients with testicular mass who underwent testis-sparing surgery: The Eurasian uro-oncology association multicenter study

Basit Öğe Kaydı
dc.authorid0000-0002-3474-3510
dc.authorid0000-0003-0906-4417
dc.contributor.authorKeşke, Murat
dc.contributor.authorCanda, Abdullah Erdem
dc.contributor.authorKaradağ, Mert Ali
dc.contributor.authorÇiftçi, Halil
dc.contributor.authorErturhan, Sakip
dc.contributor.authorKaçtan, Çağrı
dc.contributor.authorSoytaş, Mustafa
dc.contributor.authorÖzkaya, Fatih
dc.contributor.authorÖzbey, İsa
dc.contributor.authorÖrdek, Eser
dc.contributor.authorAtmaca, Ali Fuat
dc.contributor.authorYıldırım, Asıf
dc.contributor.authorŞahin, Selçuk
dc.contributor.authorÇolakoğlu, Yunus
dc.contributor.authordel Pilar Laguna Pes, Maria
dc.date.accessioned2023-09-18T09:12:36Z
dc.date.available2023-09-18T09:12:36Z
dc.date.issued2023
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Üroloji Ana Bilim Dalı
dc.description.abstractIntroduction: Herein, we analyzed the histopathological, oncological and functional outcomes of testis-sparing surgery (TSS) in patients with distinct risk for testicular cancer. Methods: This is a multicenter retrospective study on consecutive patients who underwent TSS. Patients were categorized in high- or low-risk testicular germ cell tumor (TGCT) according to the presence/absence of features compatible with testicular dysgenesis syndrome. Histology was categorized per size and risk groups. Results: TSS was performed in 83 patients (86 tumors) of them, 27 in the high-risk group. Fifty-nine patients had a non-tumoral contralateral testis present. Sixty masses and 26 masses were benign and TGCTs, respectively. No statistical differences were observed in mean age (30.9 ± 10.32 years), pathological tumor size (14.67 ± 6.7 mm) between risk groups or between benign and malignant tumors (p = 0.608). When categorized per risk groups, 22 (73.3%) and 4 (7.1%) of the TSS specimens were malignant in the high- and low-risk patient groups, respectively. Univariate analysis showed that the only independent variable significantly related to malignant outcome was previous history of TGCT. During a mean follow-up of 25.5 ± 22.7 months, no patient developed systemic disease. Local recurrence was detected in 5 patients and received radical orchiectomy. Postoperative testosterone levels remained normal in 88% of those patients with normal preoperative level. No erectile dysfunction was reported in patients with benign lesions. Conclusion: TSS is a safe and feasible approach with adequate cancer control, and preservation of sexual function is possible in 2/3 of patients harboring malignancy. Incidence of TGCT varies extremely between patients at high and low risk for TGCT requiring a careful consideration and counseling.
dc.identifier.citationKeşke, M., Canda, A. E., Karadağ, M. A., Çiftçi, H., Erturhan, S., Kaçtan, Ç. ... del Pilar Laguna Pes, M. (2023). A retrospective analysis of 83 patients with testicular mass who underwent testis-sparing surgery: The Eurasian uro-oncology association multicenter study. Urologia Internationalis. https://dx.doi.org/10.1159/000531645
dc.identifier.doi10.1159/000531645
dc.identifier.issn0042-1138
dc.identifier.issn1423-0399
dc.identifier.pmid37591208
dc.identifier.scopus2-s2.0-85170556538
dc.identifier.scopusqualityQ2
dc.identifier.urihttps://dx.doi.org/10.1159/000531645
dc.identifier.urihttps://hdl.handle.net/20.500.12511/11447
dc.identifier.wos001102611400003en_US
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorKaçtan, Çağrı
dc.institutionauthorSoytaş, Mustafa
dc.institutionauthordel Pilar Laguna Pes, Maria
dc.language.isoen
dc.publisherKarger
dc.relation.ispartofUrologia Internationalisen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectGerm Cell Testicular Cancer
dc.subjectPartial Orchiectomy
dc.subjectTesticular Tumor
dc.subjectTestis-Sparing Surgery
dc.titleA retrospective analysis of 83 patients with testicular mass who underwent testis-sparing surgery: The Eurasian uro-oncology association multicenter study
dc.typeArticle

Dosyalar

Lisans paketi
Listeleniyor 1 - 1 / 1
Küçük Resim Yok
İsim:
license.txt
Boyut:
1.44 KB
Biçim:
Item-specific license agreed upon to submission
Açıklama:
İndir

Koleksiyon

Makale Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu