Intracytoplasmic morphologically selected sperm injection, but for whom?

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dc.authorid0000-0003-3302-5004
dc.authorid0000-0003-2923-5869
dc.authorid0000-0001-6026-6052
dc.authorid0000-0002-7059-1884
dc.contributor.authorKarabulut, Seda
dc.contributor.authorAksünger, Özlem
dc.contributor.authorKorkmaz, Oya
dc.contributor.authorEren Gözel, Hilal
dc.contributor.authorKeskin, İlknur
dc.date.accessioned2019-12-23T12:26:25Z
dc.date.available2019-12-23T12:26:25Z
dc.date.issued2019
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Histoloji ve Embriyoloji Ana Bilim Dalı
dc.departmentİstanbul Medipol Üniversitesi, Rektörlük, Rejeneratif ve Restoratif Tıp Araştırmaları Merkezi (REMER)
dc.description.abstractIntracytoplasmic sperm injection (ICSI) is performed in cases of infertility by injecting a motile and morphologically normal sperm cell under a routine ×400 magnification at which is hard to distinguish morphologically healthy sperm. Recently, the use of high-powered differential interference contrast optics gave the opportunity to select a sperm under ultra-high magnification of ×10,160. The aim of the present study was to evaluate the efficacy of the intracytoplasmic morphologically selected sperm injection (IMSI) technique in different infertility populations undergoing ICSI. Main outcome measures of routine ICSI were compared with IMSI in three different groups of patients (1, non-selected; 2, male infertility; and 3, repeated implantation failure group). Results were analysed to evaluate the effects of the IMSI procedure and to find the most suitable group of patients who may benefit from the procedure. IMSI caused a significant increase in the fertilization and top quality embryo rates in the male infertility group and a significant increase in fertilization and pregnancy rates in the repeated implantation failure group, whereas no effect was observed in the non-selected group with patients of various indications. A positive effect of IMSI on the outcome of male factor infertility and repeated implantation failure patients was observed. Data observed confirmed that the application of IMSI was beneficial for a selected group of patients with male factor infertility and repeated implantation failure.
dc.identifier.citationKarabulut, S., Aksünger, Ö., Korkmaz, O., Eren Gözel, H. ve Keskin, İ. (2019). Intracytoplasmic morphologically selected sperm injection, but for whom? Zygote, 27(5), 299-304. https://doi.org/10.1017/S0967199419000297
dc.identifier.doi10.1017/S0967199419000297
dc.identifier.endpage304
dc.identifier.issn0967-1994
dc.identifier.issn1469-8730
dc.identifier.issue5
dc.identifier.scopusqualityQ4
dc.identifier.startpage299
dc.identifier.urihttps://doi.org/10.1017/S0967199419000297
dc.identifier.urihttps://hdl.handle.net/20.500.12511/4613
dc.identifier.volume27
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherCambridge University Press
dc.relation.ispartofZygoteen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/embargoedAccess
dc.subjectICSI
dc.subjectIMSI
dc.subjectSperm
dc.subjectSperm Morphology
dc.subjectSperm Selection
dc.titleIntracytoplasmic morphologically selected sperm injection, but for whom?
dc.typeArticle

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