Comparison of the visual and auditory event related potentials of parkinson's disease epatients with and without cognitive impairment

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dc.authorid0000-0003-4292-5717
dc.authorid0000-0002-0860-0524
dc.contributor.authorGüner, Dilan
dc.contributor.authorİsogğlu Alkaç, Ümmühan
dc.contributor.authorAktürk, Tuba
dc.contributor.authorHanoğlu, Lütfü
dc.contributor.authorGüntekin, Bahar
dc.date.accessioned10.07.201910:49:13
dc.date.accessioned2019-07-10T20:02:44Z
dc.date.available10.07.201910:49:13
dc.date.available2019-07-10T20:02:44Z
dc.date.issued2017
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Nöroloji Ana Bilim Dalı
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Biyofizik Ana Bilim Dalı
dc.description57th Annual Meeting of the Society-for-Psychophysiological-Research -- OCT 11-15, 2017 -- Vienna, AUSTRIA
dc.descriptionWOS: 000415045300393
dc.description.abstractAuditory event related potentials (ERPs) and visual evoked potentials (VEPs) were recorded from eight patients with Parkinson's disease, before and after a single dose of apomorphine. To assess the treatment effects, the patients' motor state, Benton visual retention test (BVRT), and digit span tests were also examined. After apomorphine, although motor performance improved, the ERP latencies were delayed and the N2-P3 ERP amplitude was significantly diminished by comparison with pretreatment values. These data suggest that apomorphine induces, besides its motor effects in patients with Parkinson's disease, a slowing down of cognitive processing. Preferential stimulation of dopamine autoreceptors in mesocortical and mesolimbic systems may represent a neural mechanism for these effects. Also, the posttreatment BVRT rotation errors significantly increased, suggesting an apomorphine induced impairment of visuospatial perception.
dc.description.sponsorshipSociety for Psychophysiological Researchen_US
dc.identifier.citationGüner, D., İsoğlu Alkaç, Ü., Aktürk, T., Hanoğlu, L. ve Güntekin, B. (2017). Comparison of the visual and auditory event related potentials of parkinson's disease epatients with and without cognitive impairment. 57th Annual Meeting of the Society-for-Psychophysiological-Research içinde (S94-S94. ss.). Vienna, Austria, October 11-15, 2017.
dc.identifier.endpageS94
dc.identifier.issn0048-5772
dc.identifier.issn1469-8986
dc.identifier.issueSupplement: 1
dc.identifier.startpageS94
dc.identifier.urihttps://hdl.handle.net/20.500.12511/3724
dc.identifier.volume54
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.language.isoen
dc.publisherWiley
dc.relation.ispartof57th Annual Meeting of the Society-for-Psychophysiological-Researchen_US
dc.relation.publicationcategoryKonferans Öğesi - Uluslararası - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectEeg
dc.subjectParkinson
dc.subjectP300
dc.subjectApomorphine Induced
dc.subjectCognitive Changes
dc.subjectComparison with Pretreatment
dc.titleComparison of the visual and auditory event related potentials of parkinson's disease epatients with and without cognitive impairment
dc.typeConference Object

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