Fully automated preoperative liver volumetry incorporating the anatomical location of the central hepatic vein

dc.authorid0000-0002-1240-7233
dc.contributor.authorKoitka, Sven
dc.contributor.authorGudlin, Phillip
dc.contributor.authorTheysohn, Jens M.
dc.contributor.authorOezcelik, Arzu
dc.contributor.authorHoyer, Dieter P.
dc.contributor.authorDayangaç, Murat
dc.contributor.authorHosch, René
dc.contributor.authorHaubold, Johannes
dc.contributor.authorFlaschel, Nils
dc.contributor.authorNensa, Felix
dc.contributor.authorMalamutmann, Eugen
dc.date.accessioned2022-10-24T11:14:14Z
dc.date.available2022-10-24T11:14:14Z
dc.date.issued2022
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Organ Nakli Ana Bilim Dalı
dc.description.abstractThe precise preoperative calculation of functional liver volumes is essential prior major liver resections, as well as for the evaluation of a suitable donor for living donor liver transplantation. The aim of this study was to develop a fully automated, reproducible, and quantitative 3D volumetry of the liver from standard CT examinations of the abdomen as part of routine clinical imaging. Therefore, an in-house dataset of 100 venous phase CT examinations for training and 30 venous phase ex-house CT examinations with a slice thickness of 5 mm for testing and validating were fully annotated with right and left liver lobe. Multi-Resolution U-Net 3D neural networks were employed for segmenting these liver regions. The Sorensen-Dice coefficient was greater than 0.9726 +/- 0.0058, 0.9639 +/- 0.0088, and 0.9223 +/- 0.0187 and a mean volume difference of 32.12 +/- 19.40 ml, 22.68 +/- 21.67 ml, and 9.44 +/- 27.08 ml compared to the standard of reference (SoR) liver, right lobe, and left lobe annotation was achieved. Our results show that fully automated 3D volumetry of the liver on routine CT imaging can provide reproducible, quantitative, fast and accurate results without needing any examiner in the preoperative work-up for hepatobiliary surgery and especially for living donor liver transplantation.
dc.description.sponsorshipProjekt DEALen_US
dc.identifier.citationKoitka, S., Gudlin, P., Theysohn, J. M., Oezcelik, A., Hoyer, D. P., Dayangaç, M. ... Malamutmann, E. (2022). Fully automated preoperative liver volumetry incorporating the anatomical location of the central hepatic vein. Scientific Reports, 12(1). https://doi.org/10.1038/s41598-022-20778-4
dc.identifier.doi10.1038/s41598-022-20778-4
dc.identifier.issn2045-2322
dc.identifier.issue1
dc.identifier.pmid36183002
dc.identifier.scopus2-s2.0-85139149187
dc.identifier.scopusqualityQ1
dc.identifier.urihttps://doi.org/10.1038/s41598-022-20778-4
dc.identifier.urihttps://hdl.handle.net/20.500.12511/9871
dc.identifier.volume12
dc.identifier.wos000862559400017en_US
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorDayangaç, Murat
dc.language.isoen
dc.publisherNature Research
dc.relation.ispartofScientific Reportsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectCentral Hepatic Vein
dc.subjectAnatomical Location
dc.subjectLiver Volumetry Incorporating
dc.titleFully automated preoperative liver volumetry incorporating the anatomical location of the central hepatic vein
dc.typeArticle

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