Effect of adenomyosis on prognosis of patients with endometrial cancer

dc.authorid0000-0001-5457-3312
dc.contributor.authorŞimşek, Erkan
dc.contributor.authorYıldız, Şükrü
dc.contributor.authorKarakaş, Sema
dc.contributor.authorGündüz, Sadık
dc.contributor.authorAkdeniz Yıldız, Özge
dc.contributor.authorÖzdemir, İsa Aykut
dc.contributor.authorYaşar, Levent
dc.date.accessioned2023-08-09T13:44:50Z
dc.date.available2023-08-09T13:44:50Z
dc.date.issued2023
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Kadın Hastalıkları ve Doğum Ana Bilim Dalı
dc.description.abstractOBJECTIVE: Our goal was to contrast the prognoses of patients with endometrial cancer who had adenomyosis against those that did not. METHODS: All patients who had received surgical staging for hysterectomy-based endometrial cancer had their medical data retrospectively examined. The analysis covered 397 patients, who were split into two groups depending on the presence of adenomyosis. Comparisons were made between patients covering type of surgery, histopathology, endometrial cancer stage, lymphovascular space invasion, presence of biochemical or histochemical markers, adjuvant therapy, presence of adenomyosis in the myometrial wall, and outcomes in terms of overall survival and disease-free survival. RESULTS: There is no statistically significant difference in the 5-year disease-free survival or overall survival rates between endometrial cancer patients with and without adenomyosis. This is based on comparisons of tumor stage, tumor diameter, histological type and grade of tumor, myometrial invasion, lymphovascular space invasion, and biochemical markers that affect the course of the disease. The median follow-up times were 61 months for the adenomyosis-positive group and 56 months for the group without adenomyosis. CONCLUSION: Coexisting adenomyosis in endometrial cancer has no bearing on survival rates and is not a prognostic factor.
dc.identifier.citationŞimşek, E., Yıldız, Ş., Karakaş, S., Gündüz, S., Akdeniz Yıldız, Ö., Özdemir, İ. A. ... Yaşar, L. (2023). Effect of adenomyosis on prognosis of patients with endometrial cancer. Revista da Associacao Medica Brasileira (1992), 69(7), e20221720-e20221720. https://dx.doi.org/10.1590/1806-9282.20221720
dc.identifier.doi10.1590/1806-9282.20221720
dc.identifier.endpagee20221720
dc.identifier.issn0104-4230
dc.identifier.issn1806-9282
dc.identifier.issue7
dc.identifier.pmid37466591
dc.identifier.scopus2-s2.0-85165519928
dc.identifier.scopusqualityQ3
dc.identifier.startpagee20221720
dc.identifier.urihttps://dx.doi.org/10.1590/1806-9282.20221720
dc.identifier.urihttps://hdl.handle.net/20.500.12511/11294
dc.identifier.volume69
dc.identifier.wos001033719400016en_US
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorÖzdemir, İsa Aykut
dc.language.isoen
dc.publisherNLM (Medline)
dc.relation.ispartofRevista da Associacao Medica Brasileira (1992)en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectAdenomyosis
dc.subjectEndometrium Cancer
dc.subjectGynecology
dc.subjectPrognosis
dc.subjectSurvival
dc.titleEffect of adenomyosis on prognosis of patients with endometrial cancer
dc.typeArticle

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