Aptamer and nanomaterial based FRET biosensors: a review on recent advances (2014–2019)

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dc.authorid0000-0002-1677-644X
dc.contributor.authorPehlivan, Zeki Semih
dc.contributor.authorTorabfam, Milad
dc.contributor.authorKurt, Hasan
dc.contributor.authorOw-Yang, Cleva
dc.contributor.authorHildebrandt, Niko
dc.contributor.authorYüce, Meral
dc.date.accessioned2019-12-24T07:29:08Z
dc.date.available2019-12-24T07:29:08Z
dc.date.issued2019
dc.departmentİstanbul Medipol Üniversitesi, Mühendislik ve Doğa Bilimleri Fakültesi, Biyomedikal Mühendisliği Bölümü
dc.description.abstractFluorescence resonance energy transfer, one of the most powerful phenomena for elucidating molecular interactions, has been extensively utilized as a biosensing tool to provide accurate information at the nanoscale. Numerous aptamer- and nanomaterial-based FRET bioassays has been developed for detection of a large variety of molecules. Affinity probes are widely used in biosensors, in which aptamers have emerged as advantageous biorecognition elements, due to their chemical and structural stability. Similarly, optically active nanomaterials offer significant advantages over conventional organic dyes, such as superior photophysical properties, large surface-to-volume ratios, photostability, and longer shelf life. In this report (with 175 references), the use of aptamer-modified nanomaterials as FRET couples is reviewed: quantum dots, upconverting nanoparticles, graphene, reduced graphene oxide, gold nanoparticles, molybdenum disulfide, graphene quantum dots, carbon dots, and metal-organic frameworks. Tabulated summaries provide the reader with useful information on the current state of research in the field.
dc.identifier.citationPehlivan, Z. S., Torabfam, M., Kurt, H., Ow-Yang, C., Hildebrandt, N. ve Yüce, M. (2019). Aptamer and nanomaterial based FRET biosensors: a review on recent advances (2014–2019). Microchimica Acta, 186(8). https://doi.org/10.1007/s00604-019-3659-3
dc.identifier.doi10.1007/s00604-019-3659-3
dc.identifier.issn0026-3672
dc.identifier.issn1436-5073
dc.identifier.issue8
dc.identifier.scopusqualityN/A
dc.identifier.urihttps://doi.org/10.1007/s00604-019-3659-3
dc.identifier.urihttps://hdl.handle.net/20.500.12511/4635
dc.identifier.volume186
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherSpringer
dc.relation.ispartofMicrochimica Actaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectBiosensors
dc.subjectssDNA
dc.subjectFRET
dc.subjectUp-Converting Nanoparticles
dc.subjectQuantum Dots
dc.subjectGold Nanoparticles
dc.subjectGraphene
dc.subjectGraphene Quantum Dots
dc.subjectCarbon Dots
dc.subjectReduced Graphene Oxide
dc.subjectMetal-Organic Framework
dc.titleAptamer and nanomaterial based FRET biosensors: a review on recent advances (2014–2019)
dc.typeArticle

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