Analysis of atherosclerosis by inductively coupled plasma optical emission spectroscopy and scanning acoustic microscopy

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dc.authorid0000-0001-6643-9364
dc.contributor.authorTanören, Bukem
dc.contributor.authorUğurlucan, Murat
dc.contributor.authorAteş Alkan, Fatma
dc.date.accessioned2020-07-27T08:42:45Z
dc.date.available2020-07-27T08:42:45Z
dc.date.issued2020
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Kalp ve Damar Cerrahisi Ana Bilim Dalı
dc.description.abstractCalcium deposition within the atherosclerotic plaques is the precursor of cardiovascular complications. Therefore, determination of levels of minerals and trace elements in blood plays an important role in assigning the stage of atherosclerosis. In this study, determination of mineral and trace element levels in atherosclerotic patients is aimed. Mineral and trace element levels within serum samples of 12 atherosclerotic patients were evaluated by Inductively Coupled Plasma Optical Emission Spectrometry (ICP-OES) and phosphorous (P), iron (Fe), magnesium (Mg) and calcium (Ca) levels were examined. Human carotid atherosclerotic plaque samples were previously screened by Scanning Acoustic Microscopy (SAM) and sound speed maps of the plaques showed higher sound speed values in the calcified regions, when compared to collagen-rich regions, indicating accumulation of calcium. Element analysis also showed increased Ca levels within serum samples. Therefore, it can be concluded that Ca deposition can be examined by ICP-OES and SAM, indicating that these techniques are confirmatory and may be combined to characterize atherosclerosis in the future.
dc.description.sponsorshipTürkiye Cumhuriyeti Kalkınma Bakanlığıen_US
dc.identifier.citationTanören, B., Uğurlucan, M. ve Ateş Alkan, F. (2020). Analysis of atherosclerosis by inductively coupled plasma optical emission spectroscopy and scanning acoustic microscopy. Biomedical Physics and Engineering Express, 6(4). https://dx.doi.org/10.1088/2057-1976/ab8e96
dc.identifier.doi10.1088/2057-1976/ab8e96
dc.identifier.issn2057-1976
dc.identifier.issue4
dc.identifier.scopusqualityQ3
dc.identifier.urihttps://dx.doi.org/10.1088/2057-1976/ab8e96
dc.identifier.urihttps://hdl.handle.net/20.500.12511/5609
dc.identifier.volume6
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherInstitute of Physics Publishing
dc.relation.ispartofBiomedical Physics and Engineering Expressen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectAtherosclerosis
dc.subjectScanning Acoustic Microscopy
dc.subjectInductively Coupled Plasma Optical Emission Spectrometry
dc.titleAnalysis of atherosclerosis by inductively coupled plasma optical emission spectroscopy and scanning acoustic microscopy
dc.typeArticle

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