Food-induced anaphylaxis in early childhood and factors associated with its severity

Basit Öğe Kaydı
dc.authorid0000-0003-1333-2648
dc.contributor.authorAydoğan, Metin
dc.contributor.authorTopal, Erdem
dc.contributor.authorYakıcı, Nalan
dc.contributor.authorAcar, Hazal Cansu
dc.contributor.authorHızlı Demirkale, Zeynep
dc.contributor.authorArga, Mustafa
dc.contributor.authorUysal, Pınar
dc.contributor.authorAydemir, Sezin
dc.contributor.authorEser Şimşek, Işıl
dc.contributor.authorTamay, Zeynep
dc.contributor.authorÇekiç, Şükrü
dc.contributor.authorÇavkaytar, Özlem
dc.contributor.authorKaplan, Fatih
dc.contributor.authorKıykım, Ayça
dc.contributor.authorÇoğurlu, Müjde Tuğba
dc.contributor.authorSüleyman, Ayşe
dc.contributor.authorYücel, Esra
dc.contributor.authorAkkelle, Emre
dc.contributor.authorHancıoğlu, Gonca
dc.contributor.authorYaşar, Adem
dc.contributor.authorTuncel, Tuba
dc.contributor.authorNacaroğlu, Hikmet Tekin
dc.contributor.authorAydoğmuş, Çiğdem
dc.contributor.authorGüler, Nermin
dc.contributor.authorÇokuğraş, Haluk
dc.contributor.authorSapan, Nihat
dc.contributor.authorYüksel, Hasan
dc.contributor.authorSancak, Recep
dc.contributor.authorErdoğan, Mehmet Sarper
dc.contributor.authorÖzdemir, Öner
dc.contributor.authorÖzdemir, Cevdet
dc.contributor.authorOrhan, Fazıl
dc.date.accessioned2021-10-06T08:39:53Z
dc.date.available2021-10-06T08:39:53Z
dc.date.issued2021
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Çocuk Sağlığı ve Hastalıkları Ana Bilim Dalı
dc.description.abstractBackground: Several factors that increase the risk of severe food-induced anaphylaxis have been identified. Objective: We aimed to determine the demographic, etiologic, and clinical features of food-induced anaphylaxis in early childhood and also any other factors associated with severe anaphylaxis. Methods:We carried out a medical chart review of anaphylaxis cases from 16 pediatric allergy and immunology centers in Turkey. Results: The data of 227 patients with 266 food-induced anaphylaxis episodes were included in the study. The median (interquartile range) age of the first anaphylaxis episode was 9 months (6-18 months); 160 of these patients were boys (70.5%). The anaphylaxis episodes were mild in 75 cases (28.2%), moderate in 154 cases (57.9%), and severe in 37 cases (13.9%). The most frequent food allergens involved were cow's milk (47.4%), nuts (16.7%), and hen's egg (15.8%). Epinephrine was administered in only 98 (36.8%) of these anaphylaxis episodes. A logistic regression analysis revealed two statistically significant factors that were independently associated with severe anaphylaxis: the presence of angioedema and hoarseness during the anaphylactic episode. Urticaria was observed less frequently in patients who developed hypotension. In addition, confusion and syncope were associated with 25.9- and 44.6-fold increases, respectively, in the risk of concomitant hypotension. Conclusion: Cow's milk, nuts, and hen's egg caused the majority of mild and moderate-to-severe anaphylaxis episodes. The presence of angioedema and hoarseness in any patient who presents with a history of food-induced anaphylaxis should alert clinicians that the reaction may be severe. In addition, the presence of confusion, syncope, or stridor probably indicates concomitant hypotension.
dc.identifier.citationAydoğan, M., Topal, E., Yakıcı, N., Acar, H. C., Hızlı Demirkale, Z., Arga, M. ... Orhan, F. (2021). Food-induced anaphylaxis in early childhood and factors associated with its severity. Allergy and Asthma Proceedings, 42(5), E135-E144. https://dx.doi.org/10.2500/aap.2021.42.210051
dc.identifier.doi10.2500/aap.2021.42.210051
dc.identifier.endpageE144
dc.identifier.issn1088-5412
dc.identifier.issn1539-6304
dc.identifier.issue5
dc.identifier.scopusqualityQ2
dc.identifier.startpageE135
dc.identifier.urihttps://dx.doi.org/10.2500/aap.2021.42.210051
dc.identifier.urihttps://hdl.handle.net/20.500.12511/8370
dc.identifier.volume42
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherOceanSide Publications Inc.
dc.relation.ispartofAllergy and Asthma Proceedingsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectAnaphylaxis
dc.subjectAngioedema
dc.subjectChildhood
dc.subjectCow's Milk
dc.subjectEpinephrine
dc.subjectFood Allergy
dc.subjectHen's Egg
dc.subjectHoarseness
dc.subjectRisk Factors
dc.subjectSeverity
dc.titleFood-induced anaphylaxis in early childhood and factors associated with its severity
dc.typeArticle

Dosyalar

Lisans paketi
Listeleniyor 1 - 1 / 1
Küçük Resim Yok
İsim:
license.txt
Boyut:
1.44 KB
Biçim:
Item-specific license agreed upon to submission
Açıklama:
İndir

Koleksiyon

Makale Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu