Clinical outcomes of selective removal to soft dentin versus firm dentin for deep caries lesions: a randomized controlled trial up to 5 years

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dc.contributor.authorGözetici Çil, Burcu
dc.contributor.authorÇetin, Tuba
dc.contributor.authorBittar, Ahmad
dc.contributor.authorÖzcan, Mutlu
dc.date.accessioned2025-12-10T13:15:27Z
dc.date.available2025-12-10T13:15:27Z
dc.date.issued2024
dc.departmentİstanbul Medipol Üniversitesi, Diş Hekimliği Fakültesi, Restoratif Diş Tedavisi Ana Bilim Dalı
dc.description.abstractObjectives: This study aimed to compare the success of selective removal to soft dentine (SRSD) with or without calcium silicate (CS) and selective removal to firm dentine (SRFD) in permanent dentition. Materials and methods: Between November 2018 and March 2020, 165 posterior deep caries lesions in 134 patients were included in the study and randomly assigned into test (n = 101) and control (n = 64) groups. The control group (n = 46) received the treatment of SRFD with CS, while the test group was further randomized into two groups to receive SRSD with CS (n = 45) and SRSD without CS (n = 45). An additional group (PE) consisted of teeth with exposed pulps during caries removal (n = 29). The primary outcome of the study was to assess the vitality of the teeth based on clinical and radiographic examination after five years. The secondary outcome of the study was to evaluate the influence of baseline variables and CS application on treatment outcome. The success rates of different treatment strategies were compared (Pearson chi-squared and Log-rank tests). The impact of baseline variables and treatment strategies on failure and dentin bridge formation was analyzed using binary logistic regression model. Results: The success rate for SRSD with or without CS (94.1–100%) was significantly higher compared to SRFD (75.8%) and PE (81.8%) after five years (P = 0.012). Failure was less likely for premolars. Cavity type and depth had an influence on dentin bridge formation. Conclusion: A five-year follow-up in this study demonstrated better clinical outcome for SRSD with or without CS compared to SRFD technique, irrespective of age, pre-op sensitivity, cavity type, radiographic depth and activity of the caries. Application of CS after SRSD in deeper cavities provided better healing in terms of dentin bridge formation. Clinical relevance: SRSD might be more advantageous over SRFD for the management of deep caries lesions.
dc.description.sponsorshipResearch Fund of Istanbul Medipol University
dc.identifier.citationGözetici Çil, B., Çetin, T., Bittar, A. ve Özcan, M. (2024). Clinical outcomes of selective removal to soft dentin versus firm dentin for deep caries lesions: a randomized controlled trial up to 5 years. Clinical Oral Investigations, 29(1). http://dx.doi.org/10.1007/s00784-024-06109-z
dc.identifier.doi10.1007/s00784-024-06109-z
dc.identifier.issn1432-6981
dc.identifier.issn1436-3771
dc.identifier.issue1
dc.identifier.pmid39702606
dc.identifier.scopus2-s2.0-85212707125
dc.identifier.scopusqualityQ1
dc.identifier.urihttp://dx.doi.org/10.1007/s00784-024-06109-z
dc.identifier.urihttps://hdl.handle.net/20.500.12511/13321
dc.identifier.volume29
dc.identifier.wosWOS:001380251800002
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorÇetin, Tuba
dc.institutionauthorBittar, Ahmad
dc.institutionauthorid0000-0001-9570-8586
dc.institutionauthorid0009-0009-3305-5298
dc.language.isoen
dc.relation.ecinfo:eu-repo/grantAgreement/EC/FP7/2019-01
dc.relation.ispartofClinical Oral Investigations
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/embargoedAccess
dc.subjectClinical Trial
dc.subjectDeep Caries Lesion
dc.subjectDental Materials
dc.subjectPermanent Teeth
dc.subjectSelective Caries Removal
dc.titleClinical outcomes of selective removal to soft dentin versus firm dentin for deep caries lesions: a randomized controlled trial up to 5 years
dc.typeArticle

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