Exploring medium- and long-term respiratory and functional sequelae in young adults post-covid-19
| dc.contributor.author | Ülker Ekşi, Büşra | |
| dc.contributor.author | Kısa, Eylül Pınar | |
| dc.contributor.author | Ertan Harputlu, Özge | |
| dc.contributor.author | Kara Kaya, Begüm | |
| dc.contributor.author | Hoşbay, Zeynep | |
| dc.contributor.author | Akıncı, Buket | |
| dc.date.accessioned | 2026-04-13T08:45:43Z | |
| dc.date.available | 2026-04-13T08:45:43Z | |
| dc.date.issued | 2025 | |
| dc.department | İstanbul Medipol Üniversitesi, Sağlık Bilimleri Fakültesi, Ergoterapi Bölümü | |
| dc.description.abstract | Background and Objectives: Long COVID-19 syndrome may cause difficulties in functionality during daily life in young people. Our objective was to investigate the respiratory and functional sequelae in young adults with asymptomatic or mild COVID-19 compared with healthy peers 3–6 months and 6–12 months after COVID-19 infection. Materials and Methods: Participants aged 18–25 who had COVID-19 within the last 3–6 months (Post-COVID Group 1, n = 25) and 6–12 months (Post-COVID Group 2, n = 25) and age–gender-matched healthy controls (n = 25) were included in this study. Respiratory functions and muscle strength were measured. Physical function was assessed with 6 min walking test (6MWT) and an Incremental Shuttle Walk Test (ISWT). The 1 min sit-to-stand test (1-MSTST) and hand grip strength (HGS) were used to assess muscle performance. Fatigue and dyspnea severity were questioned. Results: The FVC%pred (p = 0.023) and MEP (p = 0.034) were higher, and 1-MSTST repetitions were lower in Post-COVID Group-1 compared to Post-COVID Group-2 (p = 0.029). The PEF%pred (p = 0.025), MEP (p = 0.001), and ISWT distance were lower in Post-COVID Group-2 compared to healthy controls. The number of 1-MSTST repetitions and 6MWT distance were lower in Post-COVID Group-1 (p = 0.003, p = 0.001) and Post-COVID Group-2 (p = 0.003, p = 0.017) than in healthy controls. Exercise-induced blood lactate change during the ISWT, HGS, fatigue, and dyspnea were not significantly different between post-COVID groups and healthy controls. Conclusions: Young adults who pass asymptomatic or mild SARS-CoV-2 infection exhibit a decline in FVC%pred, PEF%pred, lower extremity muscle performance, and physical function within 3–6 months. In addition, the deterioration in respiratory and physical functions becomes apparent within 6–12 months. | |
| dc.description.sponsorship | Research Fund of Biruni University Biratto Directorate Project | |
| dc.identifier.citation | Ülker Ekşi, B., Kısa, E. P., Ertan Harputlu, Ö., Kara Kaya, B., Hoşbay, Z. ve Akıncı, B. (2025). Exploring medium- and long-term respiratory and functional sequelae in young adults post-covid-19. Medicina (Lithuania), 61(1). http://dx.doi.org/10.3390/medicina61010086 | |
| dc.identifier.doi | 10.3390/medicina61010086 | |
| dc.identifier.issn | 1010-660X | |
| dc.identifier.issn | 1648-9144 | |
| dc.identifier.issue | 1 | |
| dc.identifier.pmid | 39859068 | |
| dc.identifier.scopus | 2-s2.0-85215769064 | |
| dc.identifier.scopusquality | Q1 | |
| dc.identifier.uri | http://dx.doi.org/10.3390/medicina61010086 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.12511/13416 | |
| dc.identifier.volume | 61 | |
| dc.identifier.wos | WOS:001404412900001 | |
| dc.identifier.wosquality | Q1 | |
| dc.indekslendigikaynak | Web of Science | |
| dc.indekslendigikaynak | Scopus | |
| dc.indekslendigikaynak | PubMed | |
| dc.institutionauthor | Kısa, Eylül Pınar | |
| dc.institutionauthorid | 0000-0003-4707-4528 | |
| dc.language.iso | en | |
| dc.relation.ispartof | Medicina (Lithuania) | |
| dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | |
| dc.relation.tubitak | info:eu-repo/grantAgreement/TUBITAK/BAP/2020/01/19 | |
| dc.rights | info:eu-repo/semantics/openAccess | |
| dc.rights | Attribution 4.0 International | |
| dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | |
| dc.subject | Long COVID-19 | |
| dc.subject | Physical Function | |
| dc.subject | Post-COVID | |
| dc.subject | Respiratory Function | |
| dc.title | Exploring medium- and long-term respiratory and functional sequelae in young adults post-covid-19 | |
| dc.type | Article |
