A new recommendation for febrile urinary tract infection in children aged 2-24 months: Tepecik UTI Guideline-2

dc.authorid0000-0002-3582-5075
dc.contributor.authorKoyun Cezayir, Begüm
dc.contributor.authorYavaşcan, Önder
dc.contributor.authorAlaygut, Demet
dc.contributor.authorKasap Demir, Belde
dc.contributor.authorMutlubaş, Fatma
dc.contributor.authorArslansoyu Çamlar, Seçil
dc.contributor.authorAlparslan, Caner
dc.contributor.authorSoyaltın, Eren
dc.contributor.authorÖzgür, Su
dc.date.accessioned2023-01-20T09:34:03Z
dc.date.available2023-01-20T09:34:03Z
dc.date.issued2023
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Çocuk Sağlığı ve Hastalıkları Ana Bilim Dalı
dc.description.abstractAIM: Urinary tract infections (UTIs) represent a common febrile illness in infancy. The study compared two UTI guidelines in terms of number of imaging studies, presence of parenchymal damage and radiation exposure in patients with the first febrile UTI between 2 and 24?months of age. METHOD: The results of Tepecik UTI Guideline-1 used until 2012 (Group 1, n?=?105) were retrospectively compared with Tepecik UTI Guideline-2 (Group 2) used after 2013. In Group 1, urinary tract ultrasonography (US), dimercaptosuccinic acid (DMSA) and voiding cystourethrography (VCUG) were made in all patients. In Group 2, if the US result was abnormal, patients were evaluated with VCUG and DMSA. If the US was normal, only DMSA was performed. If the DMSA was abnormal, the VCUG was undergone (n: 43, 40.9%). RESULTS: The abnormal VCUG detection rate was 69.2% in Group 1 and 30.8% in Group 2 (p?=?0.09). Sensitivity and specificity of US in the diagnosis of vesicoureteral reflux (VUR) was 15.9% and 96.7% in Group 1 and 61.5% and 70.5% in Group 2, respectively. Abnormal DMSA findings were observed among 33.3% (Groups 1) and 66.7% (Groups 2) subjects, respectively (p?>?0.05). The median radiation exposure (500?mrem) of patients in Group 1 was statistically significantly higher than those in Group 2 (200?mrem) (p?<?0.001). CONCLUSION: The VCUG should not be the first examination to be considered in such patients. We think that Tepecik UTI Guideline-2 reduces unnecessary invasive procedure and radiation exposure and not missed VUR in the management of children with UTI at 2-24?months. Needs prospective follow-up studies before considering this recommendation.
dc.identifier.citationKoyun Cezayir, B., Yavaşcan, Ö., Alaygut, D., Kasap Demir, B., Mutlubaş, F. ve Arslansoyu Çamlar, S. (2023). A new recommendation for febrile urinary tract infection in children aged 2-24 months: Tepecik UTI Guideline-2. Journal of Tropical Pediatrics, 69(1). https://dx.doi.org/10.1093/tropej/fmac109
dc.identifier.doi10.1093/tropej/fmac109
dc.identifier.issn0142-6338
dc.identifier.issn1465-3664
dc.identifier.issue1
dc.identifier.pmid36625359
dc.identifier.scopus2-s2.0-85145956770
dc.identifier.scopusqualityQ3
dc.identifier.urihttps://dx.doi.org/10.1093/tropej/fmac109
dc.identifier.urihttps://hdl.handle.net/20.500.12511/10345
dc.identifier.volume69
dc.identifier.wos000911526200001en_US
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorYavaşcan, Önder
dc.language.isoen
dc.publisherNLM (Medline)
dc.relation.ispartofJournal of Tropical Pediatricsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/embargoedAccess
dc.subjectFebrile Urinary Tract Infection
dc.subjectInfancy
dc.subjectUltrasonography
dc.subjectVCUG
dc.subjectDMSA Scintigraphy
dc.titleA new recommendation for febrile urinary tract infection in children aged 2-24 months: Tepecik UTI Guideline-2
dc.typeArticle

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