Fabrication of naturel pumice/hydroxyapatite composite for biomedical engineering

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dc.contributor.authorKömür, Baran
dc.contributor.authorLohse, Tim
dc.contributor.authorCan, Hatice Merve
dc.contributor.authorKhalilova, Gülnar
dc.contributor.authorGeçimli, Zeynep Nur
dc.contributor.authorAydoğdu, Mehmet Onur
dc.contributor.authorKalkandelen, Cevriye
dc.contributor.authorStan, George E.
dc.contributor.authorŞahin, Yeşim Müge
dc.contributor.authorŞengil, Ahmet Zeki
dc.contributor.authorSüleymanoğlu, Mediha
dc.contributor.authorKuruca Erdem, Serap
dc.contributor.authorOktar, Faik Nushet
dc.contributor.authorSalman, Serdar
dc.contributor.authorEkren, Nazmi
dc.contributor.authorFicai, Anton
dc.contributor.authorGündüz, Oğuzhan
dc.date.accessioned10.07.201910:49:13
dc.date.accessioned2019-07-10T19:37:41Z
dc.date.available10.07.201910:49:14
dc.date.available2019-07-10T19:37:41Z
dc.date.issued2016
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Fizyoloji Ana Bilim Dalı
dc.description.abstractBackground: We evaluated the Bovine hydroxyapatite (BHA) structure. BHA powder was admixed with 5 and 10 wt% natural pumice (NP). Compression strength, Vickers micro hardness, Fourier transform infrared spectroscopy, scanning electron microscopy (SEM) and X-ray diffraction studies were performed on the final NP-BHA composite products. The cells proliferation was investigated by MTT assay and SEM. Furthermore, the antimicrobial activity of NP-BHA samples was interrogated. Results: Variances in the sintering temperature (for 5 wt% NP composites) between 1000 and 1300 °C, reveal about 700 % increase in the microhardness (~100 and 775 HV, respectively). Composites prepared at 1300 °C demonstrate the greatest compression strength with comparable result for 5 wt% NP content (87 MPa), which are significantly better than those for 10 wt% and those that do not include any NP (below 60 MPa, respectively). Conclusion: The results suggested the optimal parameters for the preparation of NP-BHA composites with increased mechanical properties and biocompatibility. Changes in micro-hardness and compression strength can be tailored by the tuning the NP concentration and sintering temperature. NP-BHA composites have demonstrated a remarkable potential for biomedical engineering applications such as bone graft and implant.
dc.description.sponsorshipMarmara University [FEN-B-080415-0117] [FEN-C-YLP-140115-000]en_US
dc.description.sponsorshipNIMP Core [Programme PN4501-3]en_US
dc.identifier.citationKömür, B., Lohse, T., Can, H. M., Khalilova, G., Geçimli, Z. N., Aydoğdu, M. O. ... Gündüz, O. (2016). Fabrication of naturel pumice/hydroxyapatite composite for biomedical engineering. BioMedical Engineering Online, 15(1), https://dx.doi.org/10.1186/s12938-016-0203-0
dc.identifier.doi10.1186/s12938-016-0203-0
dc.identifier.issn1475-925X
dc.identifier.issue1
dc.identifier.scopusqualityQ2
dc.identifier.urihttps://hdl.handle.net/20.500.12511/1454
dc.identifier.urihttps://dx.doi.org/10.1186/s12938-016-0203-0
dc.identifier.volume15
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherBioMed Central Ltd.
dc.relation.ispartofBioMedical Engineering Onlineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsCC0 1.0 Universal (CC0 1.0) Public Domain Dedication*
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttps://creativecommons.org/publicdomain/zero/1.0/*
dc.subjectBioceramics
dc.subjectBioinspired Composites
dc.subjectBovine Hydroxyapatite
dc.subjectNatural Pumice
dc.titleFabrication of naturel pumice/hydroxyapatite composite for biomedical engineering
dc.typeArticle

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