Stenotrophomonas maltophilia outbreak originating from a pull-out faucet in a pediatric intensive care unit in Turkey: Insights from clinical records and molecular typing

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dc.authorid0000-0003-4325-3430
dc.authorid0000-0002-3673-9670
dc.authorid0000-0001-8022-7325
dc.contributor.authorYashar, Meltem
dc.contributor.authorBaşarır, Kerem Edip
dc.contributor.authorTanrıverdi, Elif Seren
dc.contributor.authorCelep, Selçuk
dc.contributor.authorSirekbasan, Leyla
dc.contributor.authorRakıcı, Erva
dc.contributor.authorEjder, Nebahat
dc.contributor.authorMüsellim, Eda
dc.contributor.authorÇopur Çiçek, Ayşegül
dc.contributor.authorYılmaz, Mesut
dc.date.accessioned2024-06-13T11:35:53Z
dc.date.available2024-06-13T11:35:53Z
dc.date.issued2024
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Enfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Ana Bilim Dalı
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Tıbbi Mikrobiyoloji Ana Bilim Dalı
dc.description.abstractBackground: Nosocomial Stenotrophomonas maltophilia-related cases are rising and pose a threat to immunocompromised patients. Twelve patients from our pediatric intensive care unit (PICU) presented with S maltophilia-associated bloodstream infection. Methods: This outbreak investigation includes 12 patients from PICU between the ages of 2 months and 4 years (mean 16 months, 7 male). To identify the origin, samples from all possible sources throughout the hospital were collected and ran through DNA isolation and Pulse Field Gel Electrophoresis. Results: 120 samples were collected during the outbreak. 31 samples (26%) were positive for S maltophilia. 30 S maltophilia isolates were analyzed, 10 different genotypes were identified. Clustering isolates were grouped into 3 different clusters (tolerance and optimization 1.0, cutoff 90%). The largest cluster was genotype 1, which included 19 isolates, those belong to patients’ samples and a sample from a pull-out faucet inside the PICU. The Pull-out faucet was the origin of the bloodstream infection. Discussion: Pull-out faucets allow biofilm production, due its structure. Pulse Field Gel Electrophoresis identifies the transmission dynamics of the outbreak, with its high discriminatory power. Conclusions: Water sources should be monitored on a regular basis. Pull-out faucets enable bacterial overgrowth; therefore, we recommend water surveillance during outbreak investigations.
dc.identifier.citationYashar, M., Başarır, K. E., Tanrıverdi, E. S., Celep, S., Sirekbasan, L., Rakıcı, E. ... Yılmaz, M. (2024). Stenotrophomonas maltophilia outbreak originating from a pull-out faucet in a pediatric intensive care unit in Turkey: Insights from clinical records and molecular typing. American Journal of Infection Control, 52(5), 605-610. http://dx.doi.org/10.1016/j.ajic.2023.11.018
dc.identifier.doi10.1016/j.ajic.2023.11.018
dc.identifier.endpage610
dc.identifier.issn0196-6553
dc.identifier.issn1527-3296
dc.identifier.issue5
dc.identifier.pmid38043636
dc.identifier.scopus2-s2.0-85179810364
dc.identifier.scopusqualityQ1
dc.identifier.startpage605
dc.identifier.urihttp://dx.doi.org/10.1016/j.ajic.2023.11.018
dc.identifier.urihttps://hdl.handle.net/20.500.12511/12641
dc.identifier.volume52
dc.identifier.wos001233915100001en_US
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorYashar, Meltem
dc.institutionauthorBaşarır, Kerem Edip
dc.institutionauthorCelep, Selçuk
dc.institutionauthorSirekbasan, Leyla
dc.institutionauthorMüsellim, Eda
dc.institutionauthorÇopur Çiçek, Ayşegül
dc.institutionauthorYılmaz, Mesut
dc.language.isoen
dc.relation.ispartofAmerican Journal of Infection Controlen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectFaucet Aerator
dc.subjectGenotype
dc.subjectImmunocompromised Patients
dc.subjectOutbreak-Investigation
dc.subjectStenotrophomonas Maltophilia Bacteremia
dc.titleStenotrophomonas maltophilia outbreak originating from a pull-out faucet in a pediatric intensive care unit in Turkey: Insights from clinical records and molecular typing
dc.typeArticle

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