Practical performance of hippocampal tissue resection in rats in pharmacomolecular research

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dc.authorid0000-0003-2003-6337
dc.authorid0000-0002-8084-7855
dc.contributor.authorYılmaz, İbrahim
dc.contributor.authorKaraarslan, Numan
dc.contributor.authorÖzbek, Hanefi
dc.date.accessioned2021-02-19T07:21:22Z
dc.date.available2021-02-19T07:21:22Z
dc.date.issued2021
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Tıbbi Farmakoloji Ana Bilim Dalı
dc.description.abstractAIM: To explain how to resect hippocampal tissue in rats used as live mammalian subjects for the resection of fresh cerebral tissue in laboratories.MATERIAL and METHODS: Adult male Wistar-Albino rats (n=50) were used for this purpose.RESULTS: The average bodyweight of the rats was 316.4 +/- 11.71 g, and the average weight of the resected hippocampal tissues was 1.01 +/- 0.03 g; however, there were no statistically significant differences between the body weights and the hippocampal tissue weights (p>0.05). The hippocampal tissues to be used in the study were excised practically by preserving the original anatomical configuration without injury to the tissue.CONCLUSION: This paper elucidates a simple, step-by-step methodology for performance in the laboratory in order to improve the standardization of hippocampal tissue dissection.
dc.description.sponsorshipIMU-HAYDEK, as the affiliates of the Regenerative and Restorative Medical Research Centre of Istanbul Medipol Universityen_US
dc.identifier.citationYılmaz, İ., Karaarslan, N. ve Özbek, H. (2021). Practical performance of hippocampal tissue resection in rats in pharmacomolecular research. Turkish Neurosurgery, 31(1), 112-118. https://dx.doi.org/10.5137/1019-5149.JTN.31730-20.1
dc.identifier.doi10.5137/1019-5149.JTN.31730-20.1
dc.identifier.endpage118
dc.identifier.issn1019-5149
dc.identifier.issue1
dc.identifier.scopusqualityQ3
dc.identifier.startpage112
dc.identifier.urihttps://dx.doi.org/10.5137/1019-5149.JTN.31730-20.1
dc.identifier.urihttps://hdl.handle.net/20.500.12511/6564
dc.identifier.volume31
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherTurkish Neurosurgical Society
dc.relation.ispartofTurkish Neurosurgeryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/embargoedAccess
dc.subjectDissection
dc.subjectBrain
dc.subjectCerebellum
dc.subjectCortex
dc.subjectHippocampus
dc.subjectWistar-Albino
dc.subjectRat
dc.titlePractical performance of hippocampal tissue resection in rats in pharmacomolecular research
dc.typeArticle

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