Delta MELD as a predictor of early outcome in adult-to-adult living donor liver transplantation

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dc.authorid0000-0002-1240-7233
dc.contributor.authorAcar, Sencan
dc.contributor.authorAkyıldız, Murat
dc.contributor.authorGürakar, Ahmet
dc.contributor.authorTokat, Yaman
dc.contributor.authorDayangaç, Murat
dc.date.accessioned2021-01-14T12:49:33Z
dc.date.available2021-01-14T12:49:33Z
dc.date.issued2020
dc.departmentİstanbul Medipol Üniversitesi, Uluslararası Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Genel Cerrahi Ana Bilim Dalı
dc.description.abstractBackground/Alms: An increased post-operative mortality risk has been reported among patients who undergo living donor liver transplantation (LDLT) with higher model for end-stage liver disease (MELD) scores. In this study, we investigated the effect of MELD score reduction on post-operative outcomes in patients with a high MELD (>= 20) score by pre-transplant management.Materials and Methods: We retrospectively analyzed 386 LDLT cases, and patients were divided into low-MELD (<20, n=293) vs. high-MELD (>= 20, n=93) groups according to their MELD score at the time of index hospitalization. Patients in the high-MELD group were managed specifically according to a treatment algorithm in an effort to decrease the MELD score. Patients in the high-MELD group were further divided into 2 subgroups: (1) responders (n=34) to pre-transplant treatment with subsequent reduction of the MELD score by a minimum of I point vs. (2) non-responders (n=59), whose MELD score remained unchanged or further increased on the day of LDLT. Responders vs. non-responders were compared according to etiology, demographics, and survival.
dc.identifier.citationAcar, S., Akyıldız, M., Gürakar, A., Tokat, Y. ve Dayangaç, M. (2020). Delta MELD as a predictor of early outcome in adult-to-adult living donor liver transplantation. Turkish Journal of Gastroenterology, 31(11), 782-789. https://dx.doi.org/10.5152/tjg.2020.18761
dc.identifier.doi10.5152/tjg.2020.18761
dc.identifier.endpage789
dc.identifier.issn1300-4948
dc.identifier.issn2148-5607
dc.identifier.issue11
dc.identifier.scopusqualityQ3
dc.identifier.startpage782
dc.identifier.urihttps://dx.doi.org/10.5152/tjg.2020.18761
dc.identifier.urihttps://hdl.handle.net/20.500.12511/6252
dc.identifier.volume31
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherAVES
dc.relation.ispartofTurkish Journal of Gastroenterologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/embargoedAccess
dc.subjectLiving Donor Liver Transplant
dc.subjectMELD Change
dc.subjectSurvival
dc.titleDelta MELD as a predictor of early outcome in adult-to-adult living donor liver transplantation
dc.typeArticle

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