Mi196a2 T/C variant as possible predisposal factor for ankylosing spondylitis in a Turkish population

Ankylosing spondylitis (AS) is a chronic inflammatory disorder. Micro RNAs (miRNAs), small noncoding RNA molecules, can function as either oncogenes or tumor suppressor genes. Altered miRNA expression has been implicated in the pathogenesis of several diseases. Therefore, we aimed to explore the effects of miR-196a2 T/C (rs11614913) variant profile on susceptibility to AS in a Turkish population. Blood samples were collected from 78 AS patients and 79 controls.