Clinical and laboratory comparison of Covid-19 and influenza A/B in children

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dc.authorid0000-0002-6490-4530
dc.authorid0000-0002-2621-1397
dc.authorid0000-0003-4479-3404
dc.authorid0000-0003-3952-1914
dc.authorid0000-0003-2350-6381
dc.contributor.authorTemel, Hayrettin
dc.contributor.authorOkur, Mesut
dc.contributor.authorGündüz, Mehmet
dc.contributor.authorCömert, Murat
dc.contributor.authorErkesim, Remzi
dc.contributor.authorÇelebi, Merve
dc.contributor.authorİstanbullu Tosun, Ayşe
dc.contributor.authorÜlfer, Gözde
dc.date.accessioned2021-08-03T10:15:51Z
dc.date.available2021-08-03T10:15:51Z
dc.date.issued2021
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Çocuk Sağlığı ve Hastalıkları Ana Bilim Dalı
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Tıbbi Biyokimya Ana Bilim Dalı
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Tıbbi Mikrobiyoloji Ana Bilim Dalı
dc.description.abstractBackground: The clinical picture of COVID-19 shows significant similarity with influenza. In this study, it was aimed to compare the clinical and laboratory findings between pediatric patients diagnosed with COVID-19 and those with influenza A or B, and to obtain data on the differential diagnosis of COVID-19 from influenza in children. Methods: The study included 104 patients with COVID-19, 140 patients with influenza A and 135 patients with influenza B (379 patients in total) who were admitted to our tertiary hospital with symptoms of acute respiratory tract infection. Results: Fever, cough, runny nose, and pharyngeal hyperemia rates were significantly lower in patients with COVID-19 than in those with influenza A/B. The highest leukocytosis and lymphocytosis rates were seen in influenza A patients. Eosinophil levels were found significantly lower in the influenza A/B patients compared to the COVID-19 group. C-reactive protein levels were significantly higher in the influenza A/B group when compared with the COVID-19 group. The mean PDW value was significantly higher in the COVID-19 patients compared to influenza A/B. Conclusions: Our study data show that low body temperature and loss of taste and smell support the diagnosis of COVID-19, and fever, cough, pharyngeal hyperemia, and runny nose support the diagnosis of influenza. While leukocytosis and increased C-reactive protein suggest influenza, high PDW and eosinophil levels support COVID-19.
dc.identifier.citationTemel, H., Okur, M., Gündüz, M., Cömert, M., Erkesim, R., Çelebi, M. ... Ülfer, G. (2021). Clinical and laboratory comparison of Covid-19 and influenza A/B in children. Clinical Laboratory, 67(7), 1655-1661. https://dx.doi.org/10.7754/Clin.Lab.2020.201138
dc.identifier.doi10.7754/Clin.Lab.2020.201138
dc.identifier.endpage1661
dc.identifier.issn1433-6510
dc.identifier.issue7
dc.identifier.scopusqualityQ3
dc.identifier.startpage1655
dc.identifier.urihttps://dx.doi.org/10.7754/Clin.Lab.2020.201138
dc.identifier.urihttps://hdl.handle.net/20.500.12511/7661
dc.identifier.volume67
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherVerlag Klinisches Labor GmbH
dc.relation.ispartofClinical Laboratoryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectChildren
dc.subjectCOVID-19
dc.subjectInfluenza
dc.titleClinical and laboratory comparison of Covid-19 and influenza A/B in children
dc.typeArticle

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