Separation anxiety disorder among outpatients with major depressive disorder: Prevalence and clinical correlates

dc.contributor.authorYeni Elbay, Rümeysa
dc.contributor.authorGörmez, Aynur
dc.contributor.authorKılıç, Alperen
dc.contributor.authorAvcı, Selma Hilal
dc.date.accessioned2021-10-20T09:00:20Z
dc.date.available2021-10-20T09:00:20Z
dc.date.issued2021
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Ruh Sağlığı ve Hastalıkları Ana Bilim Dalı
dc.description.abstractPrior studies have reported that separation anxiety disorder (SEPAD) can continue into or may begin in adulthood. Association of SEPAD with other psychiatric disorders has been frequently examined, and high rates of co-morbidities have been found. The aim of this study was to investigate the prevalence and clinical correlation of SEPAD in adult patients undergoing treatment for major depressive disorder (MDD). The study sample was comprised of 100 outpatients. Participants underwent a DSM-5-based comprehensive assessment. Purposefully-designed semi-structured sociodemographic information and illness history forms were filled out by the researchers, and diagnoses of SEPAD were made using the Structured Clinical Interview for Separation Anxiety Symptoms, Separation Anxiety Symptom Inventory and Adult Separation Anxiety Survey. The frequency of SEPAD was 41% in patients with MDD, three-quarters of whom were adult onset. The use of new-generation antidepressants, adjunctive medications and comorbidity of other anxiety disorders were higher in patients with SEPAD (p < 0.05). SEPAD was highly prevalent, with a majority of cases starting in adulthood among patients with MDD, while SEPAD comorbidity was associated with high levels of anxiety and an increased likelihood of suboptimal response to usual depression treatment. Further studies are required to define the relevance and pathological basis for the comorbidity of SEPAD in people with MDD.
dc.identifier.citationYeni Elbay, R., Görmez, A., Kılıç, A. ve Avcı, S. H. (2021). Separation anxiety disorder among outpatients with major depressive disorder: Prevalence and clinical correlates. Comprehensive Psychiatry, 105. https://dx.doi.org/10.1016/j.comppsych.2020.152219
dc.identifier.doi10.1016/j.comppsych.2020.152219
dc.identifier.issn0010-440X
dc.identifier.issn1532-8384
dc.identifier.scopusqualityQ1
dc.identifier.urihttps://dx.doi.org/10.1016/j.comppsych.2020.152219
dc.identifier.urihttps://hdl.handle.net/20.500.12511/8482
dc.identifier.volume105
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherW.B Saunders Co-Elsevier Inc
dc.relation.ispartofComprehensive Psychiatryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 International*
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectComorbidity
dc.subjectDepression
dc.subjectPrevalence
dc.subjectSeparation Anxiety
dc.titleSeparation anxiety disorder among outpatients with major depressive disorder: Prevalence and clinical correlates
dc.typeArticle

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