Efficacy of quadrivalent HPV vaccine for vulvar condyloma recurrence

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dc.contributor.authorŞenol, Taylan
dc.contributor.authorYerçok, Yeşim
dc.contributor.authorÖzkaya, Enis
dc.contributor.authorKöse, Mehmet Faruk
dc.date.accessioned10.07.201910:49:13
dc.date.accessioned2019-07-10T19:36:02Z
dc.date.available10.07.201910:49:14
dc.date.available2019-07-10T19:36:02Z
dc.date.issued2016
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Kadın Hastalıkları ve Doğum Ana Bilim Dalı
dc.descriptionIEEE International Ultrasonics Symposium, IUS 2015
dc.description21 October 2015 through 24 October 2015
dc.description118680
dc.description.abstractAim: We tried to assess both prophylactic and therapeutic efficacies of quadrivalent vaccine for vulvar condylomas. Material and Methods: Thirty three women with vulvovaginal condylomas and variable degree of cervical preinasive lesions were treated with cauterization at gynecological oncology clinic of Zeynep Kamil Women and children’s health Training and Research hospital between 2006 to 2014. After cauterization treatment, subjects were vaccinated by quadrivalent HPV vaccine at 0, 2 and 6th months from the treatment. Subjects were followed for 48 months by repeat cervical smears/year and routine urogenital examination. Results: Among 33 cases with vulvar condylomas, there were 6 (18 %) cases with HGSIL, 4 (12 %) cases with ASCUS, 8 (24 %) cases with LGSIL and 15 (46 %) cases with normal cervical smear. Colposcopy directed biopsy revealed 3 (9 %) cases with CIN1, 1 (3 %) case with CIN 3, 29 (88 %) cases with normal histopathology. Distribution of HPV screening results were as follows:HPV 16 in 2 (6 %) cases, HPV 35 in 1 (3 %) case, HPV 56 in 1 (3 %) case, there were 18 (54 %) cases with HPV negative result and 11 (34 %) cases with low risk HPV type. Condyloma recurrence was observed in 4 (12 %) cases. There was only 1 (3 %) case of women with abnormal smear (LGSIL) in control smears during 48 months of follow up. Conclusion: In our study, we included only regularly followed women through 48 months period, and our data revealed lowered condyloma recurrence after cauterization and quadrivalent vaccination.
dc.identifier.citationŞenol, T., Yerçok, Y., Özkaya, E. ve Köse, M. F. (2016). Efficacy of quadrivalent HPV vaccine for vulvar condyloma recurrence. Türk Jinekolojik Onkoloji Dergisi, 19(2), 15-18.
dc.identifier.endpage18
dc.identifier.issn1301-8841
dc.identifier.issue2
dc.identifier.scopusqualityQ4
dc.identifier.startpage15
dc.identifier.urihttps://hdl.handle.net/20.500.12511/1038
dc.identifier.volume19
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherGüneş Kitap Kırtasiye
dc.relation.ispartofTürk Jinekolojik Onkoloji Dergisien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectCondyloma
dc.subjectHPV
dc.subjectVaccine
dc.titleEfficacy of quadrivalent HPV vaccine for vulvar condyloma recurrence
dc.title.alternativeDörtlü HPV aşisinin vulvar kondilom nüksü üzerine etkisi
dc.typeArticle

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