Synthesis, characterization, and biological properties of composites of hydroxyapatite and hexagonal boron nitride
| dc.contributor.author | Ünal, Semra | |
| dc.contributor.author | Ekren, Nazmi | |
| dc.contributor.author | Şengil, Ahmet Zeki | |
| dc.contributor.author | Oktar, Faik Nüzhet | |
| dc.contributor.author | Irmak, Ster | |
| dc.contributor.author | Oral, Özlem | |
| dc.contributor.author | Şahin, Yeşim Müge | |
| dc.contributor.author | Kılıç, Osman Fatih | |
| dc.contributor.author | Agathopoulos, Simeon | |
| dc.contributor.author | Gündüz, Oğuzhan | |
| dc.date.accessioned | 10.07.201910:49:13 | |
| dc.date.accessioned | 2019-07-10T19:50:20Z | |
| dc.date.available | 10.07.201910:49:13 | |
| dc.date.available | 2019-07-10T19:50:20Z | |
| dc.date.issued | 2018 | |
| dc.department | İstanbul Medipol Üniversitesi, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Tıbbi Mikrobiyoloji Ana Bilim Dalı | |
| dc.description | WOS: 000442988800030 | |
| dc.description | PubMed ID: 29168913 | |
| dc.description.abstract | Hydroxyapatite (HA), obtained from bovine bones, was successfully reinforced with hexagonal boron nitrite (h-BN).h-BN/HA composites, with BN content up to 1.5 wt %, were sintered at various temperatures between 1000 and 1300 degrees C, in air. Well-sintered samples were obtained after sintering at 1200 and 1300 degrees C. The presence of h-BN contributed to dense, fine, and well-crystallized microstructure. The results of X-ray diffraction analysis and FT-IR spectroscopy showed that the produced composites comprised biphasic beta-TCP/HCA (HCA: carbonate partially substituted HA). High values of mechanical properties were achieved, namely compression strength 155 MPa for the sample 0.5% h-BN/HA and Vickers microhardness of 716 HV for the samples 1.5% h-BN/HA, both sintered at 1300 degrees C. U2OS human bone osteosarcoma proliferation and cell viability showed no adverse effect in the presence of h-BN/HA, suggesting the potential use of the produced materials as safe biomaterials in bone tissue engineering. | |
| dc.identifier.citation | Ünal, S., Ekren, N., Şengil, A., Oktar, F., Irmak, S., Oral, Ö. ... Gündüz, O. (2018). Synthesis, characterization, and biological properties of composites of hydroxyapatite and hexagonal boron nitride. Journal of Biomedical Materials Research Part B-Applied Biomaterials, 106(6), 2384-2392. https://dx.doi.org/10.1002/jbm.b.34046 | |
| dc.identifier.doi | 10.1002/jbm.b.34046 | |
| dc.identifier.endpage | 2392 | |
| dc.identifier.issn | 1552-4973 | |
| dc.identifier.issn | 1552-4981 | |
| dc.identifier.issue | 6 | |
| dc.identifier.scopusquality | Q2 | |
| dc.identifier.startpage | 2384 | |
| dc.identifier.uri | https://dx.doi.org/10.1002/jbm.b.34046 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.12511/1956 | |
| dc.identifier.volume | 106 | |
| dc.identifier.wosquality | Q2 | |
| dc.indekslendigikaynak | Web of Science | |
| dc.indekslendigikaynak | Scopus | |
| dc.indekslendigikaynak | PubMed | |
| dc.language.iso | en | |
| dc.publisher | Wiley | |
| dc.relation.ispartof | Journal of Biomedical Materials Research Part B-Applied Biomaterials | en_US |
| dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | |
| dc.rights | info:eu-repo/semantics/embargoedAccess | |
| dc.subject | Composites | |
| dc.subject | Hydroxyapatite | |
| dc.subject | Bovine Bone | |
| dc.subject | Hexagonal Boron Nitride | |
| dc.subject | Bioceramic | |
| dc.title | Synthesis, characterization, and biological properties of composites of hydroxyapatite and hexagonal boron nitride | |
| dc.type | Article |
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