Synthesis, characterization, and biological properties of composites of hydroxyapatite and hexagonal boron nitride

dc.contributor.authorÜnal, Semra
dc.contributor.authorEkren, Nazmi
dc.contributor.authorŞengil, Ahmet Zeki
dc.contributor.authorOktar, Faik Nüzhet
dc.contributor.authorIrmak, Ster
dc.contributor.authorOral, Özlem
dc.contributor.authorŞahin, Yeşim Müge
dc.contributor.authorKılıç, Osman Fatih
dc.contributor.authorAgathopoulos, Simeon
dc.contributor.authorGündüz, Oğuzhan
dc.date.accessioned10.07.201910:49:13
dc.date.accessioned2019-07-10T19:50:20Z
dc.date.available10.07.201910:49:13
dc.date.available2019-07-10T19:50:20Z
dc.date.issued2018
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Tıbbi Mikrobiyoloji Ana Bilim Dalı
dc.descriptionWOS: 000442988800030
dc.descriptionPubMed ID: 29168913
dc.description.abstractHydroxyapatite (HA), obtained from bovine bones, was successfully reinforced with hexagonal boron nitrite (h-BN).h-BN/HA composites, with BN content up to 1.5 wt %, were sintered at various temperatures between 1000 and 1300 degrees C, in air. Well-sintered samples were obtained after sintering at 1200 and 1300 degrees C. The presence of h-BN contributed to dense, fine, and well-crystallized microstructure. The results of X-ray diffraction analysis and FT-IR spectroscopy showed that the produced composites comprised biphasic beta-TCP/HCA (HCA: carbonate partially substituted HA). High values of mechanical properties were achieved, namely compression strength 155 MPa for the sample 0.5% h-BN/HA and Vickers microhardness of 716 HV for the samples 1.5% h-BN/HA, both sintered at 1300 degrees C. U2OS human bone osteosarcoma proliferation and cell viability showed no adverse effect in the presence of h-BN/HA, suggesting the potential use of the produced materials as safe biomaterials in bone tissue engineering.
dc.identifier.citationÜnal, S., Ekren, N., Şengil, A., Oktar, F., Irmak, S., Oral, Ö. ... Gündüz, O. (2018). Synthesis, characterization, and biological properties of composites of hydroxyapatite and hexagonal boron nitride. Journal of Biomedical Materials Research Part B-Applied Biomaterials, 106(6), 2384-2392. https://dx.doi.org/10.1002/jbm.b.34046
dc.identifier.doi10.1002/jbm.b.34046
dc.identifier.endpage2392
dc.identifier.issn1552-4973
dc.identifier.issn1552-4981
dc.identifier.issue6
dc.identifier.scopusqualityQ2
dc.identifier.startpage2384
dc.identifier.urihttps://dx.doi.org/10.1002/jbm.b.34046
dc.identifier.urihttps://hdl.handle.net/20.500.12511/1956
dc.identifier.volume106
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherWiley
dc.relation.ispartofJournal of Biomedical Materials Research Part B-Applied Biomaterialsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/embargoedAccess
dc.subjectComposites
dc.subjectHydroxyapatite
dc.subjectBovine Bone
dc.subjectHexagonal Boron Nitride
dc.subjectBioceramic
dc.titleSynthesis, characterization, and biological properties of composites of hydroxyapatite and hexagonal boron nitride
dc.typeArticle

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim Yok
İsim:
Şengil, A..pdf
Boyut:
34.81 MB
Biçim:
Adobe Portable Document Format
Açıklama:
Tam Metin / Full Text