Topical estrogens and non-hormonal preparations for postmenopausal vulvovaginal atrophy: An EMAS clinical guide

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dc.authorid0000-0003-4067-7887
dc.contributor.authorHirschberg, Angelica Linden
dc.contributor.authorBitzer, Johannes
dc.contributor.authorCano, Antonio
dc.contributor.authorCeausu, Iuliana
dc.contributor.authorChedraui, Peter
dc.contributor.authorDurmuşoğlu, Fatih
dc.contributor.authorErkkola, Risto
dc.contributor.authorGoulis, Dimitrios G.
dc.contributor.authorKiesel, Ludwig
dc.contributor.authorLopes, Patrice
dc.contributor.authorPines, Amos
dc.contributor.authorvan Trotsenburg, Mick
dc.contributor.authorLambrinoudaki, Irene
dc.contributor.authorRees, Margaret
dc.date.accessioned2021-06-17T08:49:21Z
dc.date.available2021-06-17T08:49:21Z
dc.date.issued2021
dc.departmentİstanbul Medipol Üniversitesi, Uluslararası Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Kadın Hastalıkları ve Doğum Ana Bilim Dalı
dc.description.abstractIntroduction: Vulvovaginal atrophy (VVA) is a chronic condition caused by estrogen deficiency. It affects around 50% of postmenopausal women, reducing their general and sexual quality of life as well as the quality of their personal relationships. Aim: The aim of this clinical guide is to set out an individualized approach to the management of VVA with topical estrogens and non-hormonal preparations. Materials and methods: Literature review and consensus of expert opinion. Summary recommendations: An individualized approach is required for the management of VVA. Topical low-dose estrogens are effective and also alleviate urinary incontinence and prevent recurrent urinary tract infections. Women should not be denied long-term use of topical estrogens as long as they feel that this treatment is of benefit to them, because the safety data are reassuring. Non-hormonal preparations (lubricants and moisturizers) should be the first-line treatment for VVA in women taking adjuvant endocrine therapies for cancers considered to be hormone-dependent. They can be used over the long term.
dc.description.sponsorshipSistema de Investigacion y Desarrollo (SINDE) ; Vice-Rectorado de Investigacion & Postgrado (VRIP) of the Universidad Catolica de Santiago de Guayaquil, Guayaquil, Ecuadoren_US
dc.identifier.citationHirschberg, A. L., Bitzer, J., Cano, A., Ceausu, I., Chedraui, P., Durmuşoğlu, F. ... Rees, M. (2021). Topical estrogens and non-hormonal preparations for postmenopausal vulvovaginal atrophy: An EMAS clinical guide. Maturitas, 148, 55-61. https://dx.doi.org/10.1016/j.maturitas.2021.04.005
dc.identifier.doi10.1016/j.maturitas.2021.04.005
dc.identifier.endpage61
dc.identifier.issn0378-5122
dc.identifier.issn1873-4111
dc.identifier.scopusqualityQ1
dc.identifier.startpage55
dc.identifier.urihttps://dx.doi.org/10.1016/j.maturitas.2021.04.005
dc.identifier.urihttps://hdl.handle.net/20.500.12511/7210
dc.identifier.volume148
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherElsevier Ireland Ltd
dc.relation.ispartofMaturitasen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectNon-Hormonal Preparations
dc.subjectTopical Estrogens
dc.subjectVulvovaginal Atrophy
dc.titleTopical estrogens and non-hormonal preparations for postmenopausal vulvovaginal atrophy: An EMAS clinical guide
dc.typeArticle

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