Nonsurgical strategies to reduce mortality in patients undergoing cardiac surgery: An updated consensus process

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dc.contributor.authorLandoni, Giovanni
dc.contributor.authorLomivorotov, Vladimir
dc.contributor.authorSilvietti, Simona
dc.contributor.authorNeto, Caetanor Nigro
dc.contributor.authorPisano, Antonio
dc.contributor.authorAlvaro, Gabriele
dc.contributor.authorHajjar, Ludmilla Abrahao
dc.contributor.authorPaternoster, Gianluca
dc.contributor.authorRiha, Hynek
dc.contributor.authorMonaco, Fabrizio
dc.contributor.authorSzekely, Andrea
dc.contributor.authorLembo, Rosalba
dc.contributor.authorAslan, Nesrin A.
dc.contributor.authorAffronti, Giovanni
dc.contributor.authorLikhvantsev, Valery
dc.contributor.authorAmarelli, Cristiano
dc.contributor.authorFominskiy, Evgeny
dc.contributor.authorRedaelli, Martina Baiardo
dc.contributor.authorPutzu, Alessandro
dc.contributor.authorBaiocchi, Massimo
dc.contributor.authorMa, Jun
dc.contributor.authorBono, Giuseppe
dc.contributor.authorCamarda, Valentina
dc.contributor.authorCovello, Remo Daniel
dc.contributor.authorDi Tomasso, Nora
dc.contributor.authorLabonia, Miriam
dc.contributor.authorLeggieri, Carlo
dc.contributor.authorLobreglio, Rosetta
dc.contributor.authorMonti, Giacomo
dc.contributor.authorMura, Paolo
dc.contributor.authorScandroglio, Anna Mara
dc.contributor.authorPasero, Daniela
dc.contributor.authorTuri, Stefano
dc.contributor.authorRoasio, Agostino
dc.contributor.authorVotta, Carmine D.
dc.contributor.authorSaporito, Emanuela
dc.contributor.authorRiefolo, Claudio
dc.contributor.authorSartini, Chiara
dc.contributor.authorBrazzi, Luca
dc.contributor.authorBellomo, Rinaldo
dc.contributor.authorZangrillo, Alberto
dc.date.accessioned2021-01-15T12:09:32Z
dc.date.available2021-01-15T12:09:32Z
dc.date.issued2018
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Anesteziyoloji ve Reanimasyon Ana Bilim Dalı
dc.description.abstractObjective: A careful choice of perioperative care strategies is pivotal to improve survival in cardiac surgery. However, there is no general agreement or particular attention to which nonsurgical interventions can reduce mortality in this setting. The authors sought to address this issue with a consensus-based approach. Design: A systematic review of the literature followed by a consensus-based voting process. Setting: A web-based international consensus conference. Participants: More than 400 physicians from 52 countries participated in this web-based consensus conference. Interventions: The authors identified all studies published in peer-reviewed journals that reported on interventions with a statistically significant effect on mortality in the setting of cardiac surgery through a systematic Medline/PubMed search and contacts with experts. These studies were discussed during a consensus meeting and those considered eligible for inclusion in this study were voted on by clinicians worldwide. Measurements and Main Results: Eleven interventions finally were selected: 10 were shown to reduce mortality (aspirin, glycemic control, high-volume surgeons, prophylactic intra-aortic balloon pump, levosimendan, leuko-depleted red blood cells transfusion, noninvasive ventilation, tranexamic acid, vacuum-assisted closure, and volatile agents), whereas 1 (aprotinin) increased mortality. A significant difference in the percentages of agreement among different countries and a variable gap between agreement and clinical practice were found for most of the interventions. Conclusions: This updated consensus process identified 11 nonsurgical interventions with possible survival implications for patients undergoing cardiac surgery. This list of interventions may help cardiac anesthesiologists and intensivists worldwide in their daily clinical practice and can contribute to direct future research in the field.
dc.description.sponsorshipOrion Pharma ; Abbott Laboratories ; Pall ; Tenaxen_US
dc.identifier.citationLandoni, G., Lomivorotov, V., Silvietti, S., Neto, C. N., Pisano, A., Alvaro, G. ... Zangrillo, A. (2018). Nonsurgical strategies to reduce mortality in patients undergoing cardiac surgery: An updated consensus process. Journal of Cardiothoracic and Vascular Anesthesia, 32(1), 225-235. https://dx.doi.org/10.1053/j.jvca.2017.06.017
dc.identifier.doi10.1053/j.jvca.2017.06.017
dc.identifier.endpage235
dc.identifier.issn1053-0770
dc.identifier.issn1532-8422
dc.identifier.issue1
dc.identifier.scopusqualityQ2
dc.identifier.startpage225
dc.identifier.urihttps://dx.doi.org/10.1053/j.jvca.2017.06.017
dc.identifier.urihttps://hdl.handle.net/20.500.12511/6262
dc.identifier.volume32
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherW.B. Saunders
dc.relation.ispartofJournal of Cardiothoracic and Vascular Anesthesiaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectCardiac Surgery
dc.subjectPerioperative
dc.subjectConsensus
dc.subjectMortality
dc.subjectMortality Reduction
dc.subjectReview
dc.titleNonsurgical strategies to reduce mortality in patients undergoing cardiac surgery: An updated consensus process
dc.typeArticle

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