The association between non-alcoholic fatty liver disease and dynapenia in men diagnosed with type 2 diabetes mellitus

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dc.authorid0000-0003-0547-1883
dc.contributor.authorBulur, Atilla
dc.contributor.authorSivritepe, Rıdvan
dc.date.accessioned2023-02-03T10:10:35Z
dc.date.available2023-02-03T10:10:35Z
dc.date.issued2023
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, İç Hastalıkları Ana Bilim Dalı
dc.description.abstractBackground: Dynapenia and non-alcoholic fatty liver disease (NAFLD) are common, especially in the middle and advanced-age diabetic male population. We aimed to examine the clinical features, NAFLD severity, and parameters associated with the presence of dynapenia in type 2 diabetes mellitus (T2DM) cases. Material and Methods: One hundred thirty-five male patients diagnosed with T2DM between 45 and 65 years of age were included. Patients were staged by ultrasonography according to NAFLD status. Results: There were significant differences in muscle strength, upper arm circumference, calf circumference, and up-and-go test scores between the mild-moderate-severe and non-NAFLD groups (p < 0.001 for all). The frequency of dynapenia was lower, and arm and calf circumferences were higher in patients without NAFLD. The muscle strength, upper arm circumference, calf circumference, and up-and-go test scores were significantly lower in the dynapenic group compared to the non-dynapenic group (p < 0.005 for all). The prevalence of dynapenia increased along with the increase in NAFLD stages (p < 0.001). Conclusions: We detected a significant association between NAFLD and dynapenia in middle-aged men with T2DM. As muscle strength decreases, the amount of fat in the liver increases, and as the fat in the liver increases, muscle strength decreases.
dc.identifier.citationBulur, A. ve Sivritepe, R. (2023). The association between non-alcoholic fatty liver disease and dynapenia in men diagnosed with type 2 diabetes mellitus. Healthcare (Switzerland), 11(2). https://dx.doi.org/10.3390/healthcare11020243
dc.identifier.doi10.3390/healthcare11020243
dc.identifier.issn2227-9032
dc.identifier.issue2
dc.identifier.pmid36673611
dc.identifier.scopus2-s2.0-85146796419
dc.identifier.scopusqualityQ2
dc.identifier.urihttps://dx.doi.org/10.3390/healthcare11020243
dc.identifier.urihttps://hdl.handle.net/20.500.12511/10397
dc.identifier.volume11
dc.identifier.wos000915573300001en_US
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorSivritepe, Rıdvan
dc.language.isoen
dc.publisherMDPI
dc.relation.ispartofHealthcare (Switzerland)en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsAttribution 4.0 International*
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/*
dc.subjectType 2 Diabetes Mellitus
dc.subjectNon-Alcoholic Fatty Liver Disease
dc.subjectDynapenia
dc.titleThe association between non-alcoholic fatty liver disease and dynapenia in men diagnosed with type 2 diabetes mellitus
dc.typeArticle

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