Beyond expectations: Disease duration and psychological burden in psoriatic arthritis

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dc.authorid0000-0002-1111-3110
dc.contributor.authorKılıç, Gamze
dc.contributor.authorKılıç, Erkan
dc.contributor.authorTekeoğlu, İbrahim
dc.contributor.authorSargın, Betül
dc.contributor.authorCengiz, Gizem
dc.contributor.authorCüzdan Balta, Nihan
dc.contributor.authorAlkan, Hakan
dc.contributor.authorNas, Kemal
dc.date.accessioned2024-01-17T11:21:21Z
dc.date.available2024-01-17T11:21:21Z
dc.date.issued2023
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Fizik Tedavi ve Rehabilitasyon Ana Bilim Dalı
dc.description.abstractThis study aims to investigate the relationship between disease duration and psychological burden in PsA and to identify the risk factors associated with psychological distress. Patients with PsA who met CASPAR classification criteria enrolled by Turkish League Against Rheumatism (TLAR)-Network. Patients were categorized into three groups based on disease duration: early stage (< 5 years), middle stage (& GE; 5, < 10 years), and late stage (& GE; 10 years). All patients underwent clinical and laboratory assessment using standardized protocol and case report forms. The associations between psychological variables and clinical parameters were assessed by a multivariate analysis. Of the 1113 patients with PsA (63.9% female), 564 (%50.7) had high risk for depression and 263 (%23.6) for anxiety. The risk of psychological burden was similar across all PsA groups, and patients with a higher risk of depression and anxiety also experienced greater disease activity, poorer quality of life, and physical disability. Multivariate logistic regression revealed that female gender (OR = 1.52), PsAQoL (OR = 1.13), HAQ (OR = 1.99), FiRST score (OR = 1.14), unemployment/retired (OR = 1.48) and PASI head score (OR = 1.41) were factors that influenced the risk of depression, whereas the current or past enthesitis (OR = 1.45), PsAQoL (OR = 1.19), and FiRST score (OR = 1.26) were factors that influenced the risk of anxiety. PsA patients can experience a comparable level of psychological burden throughout the course of their disease. Several socio-demographic and disease-related factors may contribute to mental disorders in PsA. In the present era of personalized treatment for PsA, evaluating psychiatric distress can guide tailored interventions that improve overall well-being and reduce disease burden.
dc.identifier.citationKılıç, G., Kılıç, E., Tekeoğlu, İ., Sargın, B., Cengiz, G., Cüzdan Balta, N. ... Nas, K. (2023). Beyond expectations: Disease duration and psychological burden in psoriatic arthritis. Rheumatology International, 43(9), 1695-1704. https://dx.doi.org/10.1007/s00296-023-05379-2
dc.identifier.doi10.1007/s00296-023-05379-2
dc.identifier.endpage1704
dc.identifier.issn0172-8172
dc.identifier.issn1437-160X
dc.identifier.issue9
dc.identifier.pmid37418001
dc.identifier.scopus2-s2.0-85164103430
dc.identifier.scopusqualityQ2
dc.identifier.startpage1695
dc.identifier.urihttps://dx.doi.org/10.1007/s00296-023-05379-2
dc.identifier.urihttps://hdl.handle.net/20.500.12511/12162
dc.identifier.volume43
dc.identifier.wos001024953900001en_US
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorTolu, Sena
dc.language.isoen
dc.publisherSpringer
dc.relation.ispartofRheumatology Internationalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/embargoedAccess
dc.subjectAnxiety
dc.subjectArthritis
dc.subjectPsoriatic
dc.subjectDepression
dc.subjectRheumatic Diseases
dc.subjectQuality of Life
dc.titleBeyond expectations: Disease duration and psychological burden in psoriatic arthritis
dc.typeArticle

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