Comparison of intravenous ibuprofen and paracetamol for postoperative pain management after laparoscopic sleeve gastrectomy. A randomized controlled study

dc.authorid0000-0002-3245-6614
dc.authorid0000-0002-5580-5960
dc.authorid0000-0003-0811-4945
dc.authorid0000-0003-0428-2511
dc.contributor.authorÇiftçi, Bahadır
dc.contributor.authorEkinci, Mürsel
dc.contributor.authorÇelik, Erkan Cem
dc.contributor.authorKaçıroğlu, Ahmet
dc.contributor.authorKarakaya, Muhammet Ahmet
dc.contributor.authorDemiraran, Yavuz
dc.contributor.authorÖzdenkaya, Yaşar
dc.date.accessioned10.07.201910:49:13
dc.date.accessioned2019-07-10T19:49:40Z
dc.date.available10.07.201910:49:13
dc.date.available2019-07-10T19:49:40Z
dc.date.issued2019
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Anesteziyoloji ve Reanimasyon Ana Bilim Dalı
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Genel Cerrahi Ana Bilim Dalı
dc.descriptionWOS: 000462182400003
dc.descriptionPubMed ID: 30474791
dc.description.abstractBackground Laparoscopic sleeve gastrectomy (LSG) is defined as the first-step bariatric surgery for the treatment of obesity. Opioid analgesics are often preferred for pain management because of their strong analgesic potentials. However, opioids have undesirable adverse effects. Objectives The objective of this study is to evaluate and compare the influence of IV forms of ibuprofen and paracetamol on pain management and opioid consumption on patients undergoing LSG surgery. Setting This study was conducted at Istanbul Medipol University Hospital. Methods Patients were stratified into three groups. Group I (group ibuprofen, n = 30) was administered 800 mg of IV ibuprofen, group P (group paracetamol, n = 30) was administered 1000 mg of IV paracetamol, and group C (control group, n = 30) was given 100 ml of saline solution. We evaluated opioid consumption and VAS scores postoperatively. Results This study included 90 patients who underwent LSG. The use of rescue medication in group I was statistically lower than the other groups. VAS scores in group I and group P at recovery and at 2, 4, 8, 12, and 24 h were lower than those in group C. In particular, the VAS scores in group I at the first 2 h postoperatively were significantly lower than those in group P (p <0.05). Opioid consumption in group C was significantly higher than the other groups (p <0.05). Conclusion Our study suggested that IV ibuprofen resulted in lower pain scores compared to paracetamol by reducing postoperative opioid use in the first 24 h in patients undergoing LSG surgery.
dc.identifier.citationÇiftçi, B., Ekinci, M., Çelik, E., C., Kaçıroğlu, A., Karakaya, M. A., Demiraran, Y. ve Özdenkaya, Y. (2019). Comparison of intravenous ibuprofen and paracetamol for postoperative pain management after laparoscopic sleeve gastrectomy. A randomized controlled study. Obesity Surgery, 29(3), 765-770. https://dx.doi.org/10.1007/s11695-018-3613-1
dc.identifier.doi10.1007/s11695-018-3613-1
dc.identifier.endpage770
dc.identifier.issn0960-8923
dc.identifier.issn1708-0428
dc.identifier.issue3
dc.identifier.scopusqualityQ1
dc.identifier.startpage765
dc.identifier.urihttps://dx.doi.org/10.1007/s11695-018-3613-1
dc.identifier.urihttps://hdl.handle.net/20.500.12511/1708
dc.identifier.volume29
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherSpringer
dc.relation.ispartofObesity Surgeryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/embargoedAccess
dc.subjectLaparoscopic Sleeve Gastrectomy
dc.subjectAnalgesia
dc.subjectIbuprofeny
dc.titleComparison of intravenous ibuprofen and paracetamol for postoperative pain management after laparoscopic sleeve gastrectomy. A randomized controlled study
dc.typeArticle

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