Factors affecting survival in operated gastric cancer

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dc.authorid0000-0001-6406-4095
dc.contributor.authorSakin, Ayşegül
dc.contributor.authorŞahin, Süleyman
dc.contributor.authorSakin, Abdullah
dc.contributor.authorAldemir, Mehmet Naci
dc.contributor.authorSakoğlu, Nevin
dc.contributor.authorBayram, İrfan
dc.contributor.authorKotan, Mehmet Çetin
dc.date.accessioned2022-12-09T08:46:19Z
dc.date.available2022-12-09T08:46:19Z
dc.date.issued2023
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Genel Cerrahi Ana Bilim Dalı
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, İç Hastalıkları Ana Bilim Dalı
dc.description.abstractIn this study, our aim was to determine the possible effects of Helicobacter pylori (HP), chronic atrophic gastritis (CAG), and gastrointestinal metaplasia (GIM) on survival in operated bowel type gastric cancer patients (INT-GC). Among 548 patients, 347(63.3%) were male. The median age was 57 years. Disease-free survival (DFS) and overall survival (OS) were significantly shorter in patients with GIM than those in patients without GIM (log rank, P = 0.003 and log rank P = 0.003, respectively). Multivariate analysis showed that presence of GIM (HR, 2.1) was found to be an independent factor of worse DFS. In our study, stage pIII patients with GIM had significantly shorter DFS and OS than those without GIM (log rank p = 0.008 and log rank p = 0.001, respectively). However, in subgroup analysis of patients with GIM, there was no significant DFS and OS difference between patients with stage pI and pII disease (log rank p = 0.999, log rank p = 0.184 vs. log rank p = 0.409, log rank p = 0.281, respectively).
dc.identifier.citationSakin, A., Şahin, S., Sakin, A., Aldemir, M. N., Sakoğlu, N., Bayram, İ. ... Kotan, M. Ç. (2023). Factors affecting survival in operated gastric cancer. Surgical Oncology, 46. https://doi.org/10.1016/j.suronc.2022.101887
dc.identifier.doi10.1016/j.suronc.2022.101887
dc.identifier.issn0960-7404
dc.identifier.issn1879-3320
dc.identifier.pmid36455334
dc.identifier.scopus2-s2.0-85142830832
dc.identifier.scopusqualityN/A
dc.identifier.urihttps://doi.org/10.1016/j.suronc.2022.101887
dc.identifier.urihttps://hdl.handle.net/20.500.12511/10100
dc.identifier.volume46
dc.identifier.wos000976253700001en_US
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorSakin, Abdullah
dc.institutionauthorSakoğlu, Nevin
dc.language.isoen
dc.publisherElsevier Ltd
dc.relation.ispartofSurgical Oncologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/embargoedAccess
dc.subjectBiomarker
dc.subjectGastric Atrophy
dc.subjectGastric Cancer
dc.subjectGastric Intestinal Metaplasia
dc.subjectHelicobacter Pylori
dc.subjectSurvival
dc.titleFactors affecting survival in operated gastric cancer
dc.typeArticle

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