Galectin-3 and plasma cytokines in patients with acute myocardial infarction

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dc.contributor.authorAlturfan, Ahmet Ata
dc.contributor.authorBaşar, Işık
dc.contributor.authorEmekli-Alturfan, Ebru
dc.contributor.authorAyan, Faruk
dc.contributor.authorKoldaş, Lale
dc.contributor.authorEmekli, Nesrin
dc.date.accessioned10.07.201910:49:13
dc.date.accessioned2019-07-10T20:01:37Z
dc.date.available10.07.201910:49:13
dc.date.available2019-07-10T20:01:37Z
dc.date.issued2014
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Tıbbi Biyokimya Ana Bilim Dalı
dc.descriptionWOS: 000343954700009
dc.descriptionPubMed ID: 25316666
dc.description.abstractObjective: To investigate the concentrations of plasma cytokines and Galectin-3 (Gal-3) as inflammatory markers in patients with acute myocardial infarction (AMI). Methods: The study population consisted of 29 patients with AMI and 29 healthy control subjects. We measured Gal-3, tumor necrosis factor alpha (TNF-alpha), and interleukin-6 (IL-6) levels in plasma using enzyme-linked immunosorbent assays (ELISAs). We measured levels of C-reactive protein (CRP) via the nephelometric method. Results: Patients with AMI showed significantly higher plasma Gal-3, TNF-alpha, and IL-6 levels compared with controls. Gal-3 levels were positively and significantly correlated with plasma IL-6, TNF-alpha, and CRP levels in the control and patient groups. Conclusion: Our findings suggest that Gal-3 can be a new circulating biomarker of inflammation associated with AMI.
dc.identifier.citationAlturfan, A. A., Başar, I., Emekli-Alturfan, E., Ayan, F., Koldaş, L. ve Emekli, N. (2014). Galectin-3 and plasma cytokines in patients with acute myocardial infarction. Labmedicine, 45(4), 332-337. https://dx.doi.org/10.1309/LM3JZKBDA7D4QFOC
dc.identifier.doi10.1309/LM3JZKBDA7D4QFOC
dc.identifier.endpage337
dc.identifier.issn0007-5027
dc.identifier.issn1943-7730
dc.identifier.issue4
dc.identifier.scopusqualityN/A
dc.identifier.startpage332
dc.identifier.urihttps://dx.doi.org/10.1309/LM3JZKBDA7D4QFOC
dc.identifier.urihttps://hdl.handle.net/20.500.12511/3370
dc.identifier.volume45
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherAmerican Society for Clinical Pathology
dc.relation.ispartofLabmedicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectGalectin-3
dc.subjectAMI
dc.subjectInflammation
dc.subjectCytokines
dc.subjectCRP
dc.subjectTNF-Alpha
dc.titleGalectin-3 and plasma cytokines in patients with acute myocardial infarction
dc.typeArticle

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