Seminal oxidation-reduction potential as a possible indicator of impaired sperm parameters in Turkish population

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dc.authorid0000-0003-3302-5004
dc.authorid0000-0003-2923-5869
dc.authorid0000-0002-7059-1884
dc.contributor.authorKarabulut, Seda
dc.contributor.authorKorkmaz, Oya
dc.contributor.authorYılmaz, Elif
dc.contributor.authorKeskin, İlknur
dc.date.accessioned2021-04-07T10:36:05Z
dc.date.available2021-04-07T10:36:05Z
dc.date.issued2021
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Histoloji ve Embriyoloji Ana Bilim Dalı
dc.description.abstractOxidative stress (OS) has been shown to have a key role in male infertility. Recently, a new measurement method has been developed to measure the overall oxidation-reduction potential (ORP) in a semen sample known as the MiOXSYS system. The aim of this study was to investigate the correlation of sperm parameters with oxidative stress levels determined by ORP and to evaluate whether the current limit is able to distinguish abnormal sperm parameters from normal ones in Turkish population. Semen samples of 121 patients who applied for infertility investigation were divided into two groups as (OS +; n:39) and (OS -; n:82). Semen parameters were compared between groups. Sperm concentration, total motility and progressive motility were found to be significantly lower in OS (+) patients compared to those OS (-), while immotile sperm count was significantly higher in OS (+) patients. Oxidative stress determined by MiOXSYS system was found to be related to reduced sperm parameters in Turkish population, which may be used as an indicator of poor sperm parameters and a support to routine semen analysis. In addition, recommended reference value was found to be reliable in distinguishing normal from impaired semen parameters.
dc.identifier.citationKarabulut, S., Korkmaz, O., Yılmaz, E. ve Keskin, İ. (2021). Seminal oxidation-reduction potential as a possible indicator of impaired sperm parameters in Turkish population. Andrologia, 53(2). https://dx.doi.org/10.1111/and.13956
dc.identifier.doi10.1111/and.13956
dc.identifier.issn0303-4569
dc.identifier.issn1439-0272
dc.identifier.issue2
dc.identifier.scopusqualityQ2
dc.identifier.urihttps://dx.doi.org/10.1111/and.13956
dc.identifier.urihttps://hdl.handle.net/20.500.12511/6713
dc.identifier.volume53
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherWiley
dc.relation.ispartofAndrologiaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/embargoedAccess
dc.subjectMiOXSYS
dc.subjectOxidation&#8211
dc.subjectReduction Potential
dc.subjectOxidative Stress
dc.subjectSeminal Plasma
dc.subjectSperm
dc.titleSeminal oxidation-reduction potential as a possible indicator of impaired sperm parameters in Turkish population
dc.typeArticle

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