Bioprosthetic aortic valve thrombosis under effective direct oral anticoagulant therapy

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dc.authorid0000-0001-5825-8627
dc.authorid0000-0003-1207-8692
dc.contributor.authorGüler, Arda
dc.contributor.authorErata, Yunus Emre
dc.contributor.authorAydın, Sinem
dc.contributor.authorGüneş, Hacı Murat
dc.contributor.authorBabur Güler, Gamze
dc.date.accessioned2024-01-10T11:25:08Z
dc.date.available2024-01-10T11:25:08Z
dc.date.issued2023
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Kardiyoloji Ana Bilim Dalı
dc.description.abstractWith the increase in transcatheter procedures, the use of bioprosthetic valves has become more frequent in clinical practice. However, the optimal antithrombotic management of patients with bioprosthetic valves remains controversial. In this case report, we describe a patient with a bioprosthetic aortic valve who developed a thrombus while receiving effective dose direct oral anticoagulant (DOAC) therapy. A 73-year-old male patient with a bioprosthetic aortic valve replacement 2 years prior presented with a mobile thrombus and early degeneration of the valve, detected during routine follow-up while being treated with apixaban. Although the valve thrombus regressed after switching to a different anticoagulant drug, we observed that the decreased but still high gradient persisted due to the early degeneration. Anticoagulant management of bioprosthetic valve patients demands careful attention. Although evidence supporting the use of DOACs is growing, close patient follow-up and further evaluation in case of doubt remain critical. The development of a thrombus in a bioprosthetic valve patient who is receiving anticoagulation therapy, as in this case, highlights the need for optimal management to prevent thromboembolic complications and valve degeneration.
dc.identifier.citationGüler, A., Erata, Y. E., Aydın, S., Güneş, H. M. ve Babur Güler, G. (2023). Bioprosthetic aortic valve thrombosis under effective direct oral anticoagulant therapy. Echocardiography: A Journal of Cardiovascular Ultrasound and Allied Techniques, 40(9), 983-988. https://dx.doi.org/10.1111/echo.15642
dc.identifier.doi10.1111/echo.15642
dc.identifier.endpage988
dc.identifier.issn0742-2822
dc.identifier.issn1540-8175
dc.identifier.issue9
dc.identifier.pmid37363827
dc.identifier.scopus2-s2.0-85162898076
dc.identifier.scopusqualityQ3
dc.identifier.startpage983
dc.identifier.urihttps://dx.doi.org/10.1111/echo.15642
dc.identifier.urihttps://hdl.handle.net/20.500.12511/12118
dc.identifier.volume40
dc.identifier.wos001013176900001en_US
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorGüneş, Hacı Murat
dc.institutionauthorBabur Güler, Gamze
dc.language.isoen
dc.publisherWiley
dc.relation.ispartofEchocardiography: A Journal of Cardiovascular Ultrasound and Allied Techniquesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectBioprosthetic Aortic Valve
dc.subjectDOAC
dc.subjectValve Thrombosis
dc.titleBioprosthetic aortic valve thrombosis under effective direct oral anticoagulant therapy
dc.typeArticle

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