fNIRS-based evaluation of the impact of SARS-CoV-2 infection central auditory processing

Yaman, Handan; Yılmaz, Oğuz; Hanoğlu, Lütfü; Bayazıt, Yıldırım

fNIRS-based evaluation of the impact of SARS-CoV-2 infection central auditory processing

dc.authorid	0000-0003-3075-8536
dc.authorid	0000-0003-1884-0246
dc.authorid	0000-0003-4292-5717
dc.contributor.author	Yaman, Handan
dc.contributor.author	Yılmaz, Oğuz
dc.contributor.author	Hanoğlu, Lütfü
dc.contributor.author	Bayazıt, Yıldırım
dc.date.accessioned	2024-01-18T11:59:25Z
dc.date.available	2024-01-18T11:59:25Z
dc.date.issued	2023
dc.department	İstanbul Medipol Üniversitesi, Sağlık Bilimleri Fakültesi, Odyoloji Bölümü
dc.department	İstanbul Medipol Üniversitesi, Rektörlük, Sağlık Bilim ve Teknolojileri Araştırma Enstitüsü
dc.department	İstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Nöroloji Ana Bilim Dalı
dc.description.abstract	ObjectivesCoronavirus disease-2019 due to SARS-CoV-2 infection has been associated with neurological and neuropsychiatric illnesses as well as auditory system problems. In this study, we aimed to evaluate the impact of SARS-CoV-2 infection on the central auditory system by assessing the hemodynamic activation changes using functional near-infrared spectroscopy (fNIRS).MethodsThree participants who had SARS-CoV-2 infection (study group) and four participants who had no SARS-CoV-2 infection (control group) were included in the study. During the auditory oddball task in which two different frequencies of tonal stimulation were presented at 80 dB HL, the participants were asked to pay attention to the rare tonal stimulation and mentally count these target stimuli throughout the task. During this task, oxygenated hemodynamic response functions were evaluated with fNIRS.ResultsSignificantly increased oxygenated hemodynamic responses were observed in both groups during the task (p < .05), which was significantly higher in the study group (p < .05). Significantly more HbO activation was observed in the vmPFC, superior temporal gyrus, and medial temporal gyrus in the study group compared to controls (p < .05). Significantly higher hemodynamic activation was observed in the right hemisphere in both groups, which was significantly higher in the study group (p < .05).ConclusionSARS-CoV-2 infections may impact on central auditory processing or auditory attention due to changes in oxyhemoglobin levels in the frontal and temporal brain regions. It seems that SARS-CoV-2 infection is associated with an additional load on neural activity, and difficulties in focusing in auditory attention, following speech and hearing in noise as well as increased effort to perceive auditory cues.
dc.identifier.citation	Yaman, H., Yılmaz, O., Hanoğlu, L. ve Bayazıt, Y. (2023). fNIRS-based evaluation of the impact of SARS-CoV-2 infection central auditory processing. Brain and Behavior, 13(12). https://dx.doi.org/10.1002/brb3.3303
dc.identifier.doi	10.1002/brb3.3303
dc.identifier.issn	2162-3279
dc.identifier.issue	12
dc.identifier.pmid	37908040
dc.identifier.scopus	2-s2.0-85175459579
dc.identifier.scopusquality	Q2
dc.identifier.uri	https://dx.doi.org/10.1002/brb3.3303
dc.identifier.uri	https://hdl.handle.net/20.500.12511/12172
dc.identifier.volume	13
dc.identifier.wos	001095782400001	en_US
dc.identifier.wosquality	Q2
dc.indekslendigikaynak	Web of Science
dc.indekslendigikaynak	Scopus
dc.indekslendigikaynak	PubMed
dc.institutionauthor	Yaman, Handan
dc.institutionauthor	Yılmaz, Oğuz
dc.institutionauthor	Hanoğlu, Lütfü
dc.language.iso	en
dc.publisher	Wiley
dc.relation.ispartof	Brain and Behavior	en_US
dc.relation.publicationcategory	Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rights	Attribution 4.0 International	*
dc.rights	info:eu-repo/semantics/openAccess
dc.rights.uri	https://creativecommons.org/licenses/by/4.0/	*
dc.subject	Auditory Attention
dc.subject	fNIRS
dc.subject	Oddball Paradigm
dc.subject	SARS-CoV-2
dc.title	fNIRS-based evaluation of the impact of SARS-CoV-2 infection central auditory processing
dc.type	Article