Pramipexole responsive neck numbness: The therapeutic role of dopamine agonists in the spinal cord indicating to a common spinal pathophysiology with restless leg syndrome (RLS)?

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dc.authorid0000-0002-9704-6173
dc.authorid0000-0003-4292-5717
dc.contributor.authorYuluğ, Burak
dc.contributor.authorHanoğlu, Lütfü
dc.date.accessioned2020-07-17T07:25:03Z
dc.date.available2020-07-17T07:25:03Z
dc.date.issued2016
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Nöroloji Ana Bilim Dalı
dc.description.abstractBackground: There is still speculative data regarding the role of spinal dopaminergic neurotransmission in restless leg syndrome (RLS). Methods: We evaluated the therapeutic role of pramipexole in a patient with cervical disc prolapsus who exceptionally presented with neck restlessness. Results: We have found that pramipexole leads to a significant improvement in restlessness symptoms in the neck region. Discussion: The therapeutic role of pramipexole may not only suggest secondary deficits due to spinal pathologies but also indicate that specialized spinal dopaminergic neurons may play an important role in the pathogenesis of region specific restlessness symptomatology.
dc.identifier.citationYuluğ, B. ve Hanoğlu, L. (2016). Pramipexole responsive neck numbness: The therapeutic role of dopamine agonists in the spinal cord indicating to a common spinal pathophysiology with restless leg syndrome (RLS)? Current Clinical Pharmacology, 11(3), 221-222. https://dx.doi.org/10.2174/1574884711666160719162015
dc.identifier.doi10.2174/1574884711666160719162015
dc.identifier.endpage222
dc.identifier.issn1574-8847
dc.identifier.issn2212-3938
dc.identifier.issue3
dc.identifier.scopusqualityQ1
dc.identifier.startpage221
dc.identifier.urihttps://dx.doi.org/10.2174/1574884711666160719162015
dc.identifier.urihttps://hdl.handle.net/20.500.12511/5539
dc.identifier.volume11
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherBentham Science Publishers
dc.relation.ispartofCurrent Clinical Pharmacologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectPramipexole
dc.subjectDopamine
dc.subjectPathophysiology
dc.titlePramipexole responsive neck numbness: The therapeutic role of dopamine agonists in the spinal cord indicating to a common spinal pathophysiology with restless leg syndrome (RLS)?
dc.typeArticle

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