Fatty liver disease might increase the risk of abdominal operation in patients with fatty liver and the prevalence of cancer in first-degree relatives

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dc.authorid0000-0001-9658-7560
dc.contributor.authorBaşaranoğlu, Metin
dc.contributor.authorCanbakan, Billur
dc.contributor.authorYıldız, Kemal
dc.contributor.authorCeylan, Bahadır
dc.contributor.authorBaysal, Birol
dc.contributor.authorUysal, Ömer
dc.contributor.authorŞentürk, Hakan
dc.date.accessioned10.07.201910:49:13
dc.date.accessioned2019-07-10T20:03:44Z
dc.date.available10.07.201910:49:13
dc.date.available2019-07-10T20:03:44Z
dc.date.issued2014
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Enfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Ana Bilim Dalı
dc.description63rd Annual Meeting of the American-Association-for-the-Study-of-Liver-Disease (AASLD) -- NOV 09-13, 2012 -- Boston, MA
dc.descriptionWOS: 000353553700026
dc.descriptionPubMed ID: 25910292
dc.description.abstractBackground/Aims: We investigated the risk of abdominal operation in patients with fatty liver and the risk of any cancer in first-degree relatives of patients with fatty liver. Materials and Methods: We evaluated 105 patients with nonalcoholic fatty liver disease (NAFLD), 121 patients with biopsy-proven hepatitis C (61 patients with fatty liver and 60 patients without fatty liver), 50 patients with inflammatory bowel disease (IBD), and 109 patients with dyspepsia. Results: There was no difference in sex, mean age, and marital status among the groups except that patients with IBD were younger than the others (p<0.001). The frequency of cancer among family members was 18% in IBD, 9% in dyspepsia, 28% in hepatitis C with steatosis, 21.5% in hepatitis C without steatosis, and 27% in NAFLD (p=0.006). Then, we divided the study group into two groups as follows: group 1: (IBD + dyspepsia + hepatitis C without steatosis) and group 2: (hepatitis C with steatosis + NAFLD). We found that the frequency of cancer was 16% in group 1 versus 24.4 % in group 2 (p=0.037). We also investigated the risk of abdominal operation in patients with fatty liver. The results were as follows: 33% in group without fatty liver versus 43% in group with fatty liver (p=0.043). Conclusion: Understanding the underlying causes of fatty liver forms might decrease the cancer frequency in the population and number of operations in patients with fatty liver.
dc.description.sponsorshipAmerican Association for the Study of Liver Diseasesen_US
dc.identifier.citationBaşaranoğlu, M., Canbakan, B., Yıldız, K., Ceylan, B., Baysal, B., Uysal, Ö. ... Şentürk, H. (2014). Fatty liver disease might increase the risk of abdominal operation in patients with fatty liver and the prevalence of cancer in first-degree relatives. Turkish Journal of Gastroenterology, 25(Supplement: 1), 138-141. https://dx.doi.org/10.5152/tjg.2014.7674
dc.identifier.doi10.5152/tjg.2014.7674
dc.identifier.endpage141
dc.identifier.issn1300-4948
dc.identifier.issn2148-5607
dc.identifier.issueSupplement: 1
dc.identifier.scopusqualityQ3
dc.identifier.startpage138
dc.identifier.urihttps://dx.doi.org/10.5152/tjg.2014.7674
dc.identifier.urihttps://hdl.handle.net/20.500.12511/3932
dc.identifier.volume25
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherAVES
dc.relation.ispartofTurkish Journal of Gastroenterologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectAbdominal Operation
dc.subjectCancer
dc.subjectDyspepsia
dc.subjectFatty Liver
dc.subjectHepatitis C
dc.subjectNonalcoholic
dc.titleFatty liver disease might increase the risk of abdominal operation in patients with fatty liver and the prevalence of cancer in first-degree relatives
dc.typeArticle

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