Serum and aqueous concentrations of inflammatory markers in diabetic macular edema

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dc.authorid0000-0001-5335-3860
dc.authorid0000-0001-9829-7268
dc.contributor.authorKocabora, Selim
dc.contributor.authorTelli, Mehmet Erdem
dc.contributor.authorFazıl, Korhan
dc.contributor.authorErdur Karaman, Sevil
dc.contributor.authorÖzsütçü, Mustafa
dc.contributor.authorÇekiç, Osman
dc.contributor.authorÖzbilen, Kemal Turgay
dc.date.accessioned10.07.201910:49:13
dc.date.accessioned2019-07-10T20:02:12Z
dc.date.available10.07.201910:49:13
dc.date.available2019-07-10T20:02:12Z
dc.date.issued2016
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Göz Hastalıkları Ana Bilim Dalı
dc.descriptionWOS: 000385532100013
dc.descriptionPubMed ID: 26400051
dc.description.abstractPurpose: To investigate the relationship between the serum and aqueous levels of inflammatory markers and diabetic macular edema (DME).Methods: The study included four patient groups: the healthy control group (n=23 eyes); the diabetic control group (n=22 eyes); the groups with and without DME (n=20 eyes and n=22 eyes, respectively). The patients were evaluated based on their serum levels of HbA(1c), C-reactive protein (CRP) and serum and aqueous levels of tumor necrosis factor-alpha (TNF-).Results: Statistically significant differences were present for the serum CRP levels and for the aqueous TNF- levels between the healthy control group and the group with DME (p=0.004 and p=0.03, respectively); for the serum TNF- levels between the healthy control group and the groups without and with DME (p=0.009 and p=0.001, respectively).Conclusions: Increased serum levels of CRP and serum and aqueous levels of TNF- in DME suggest that inflammation is involved in the pathogenesis of DME.
dc.identifier.citationKocabora, S., Telli, M. E., Fazıl, K., Erdur Karaman, S., Özsütçü, M., Çekiç, O. ... Özbilen, K. T. (2016). Serum and aqueous concentrations of inflammatory markers in diabetic macular edema. Ocular Immunology And Inflammation, 24(5), 549-554. https://dx.doi.org/10.3109/09273948.2015.1034804
dc.identifier.doi10.3109/09273948.2015.1034804
dc.identifier.endpage554
dc.identifier.issn0927-3948
dc.identifier.issn1744-5078
dc.identifier.issue5
dc.identifier.scopusqualityQ2
dc.identifier.startpage549
dc.identifier.urihttps://dx.doi.org/10.3109/09273948.2015.1034804
dc.identifier.urihttps://hdl.handle.net/20.500.12511/3583
dc.identifier.volume24
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherTaylor & Francis Inc
dc.relation.ispartofOcular Immunology And Inflammationen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectC-reactive Protein
dc.subjectDiabetic Retinopathy
dc.subjectInflammation
dc.subjectMacular Wdema
dc.subjectTumor Necrosis Factor-Alpha
dc.titleSerum and aqueous concentrations of inflammatory markers in diabetic macular edema
dc.typeArticle

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