Real-time elastography for differentiation of breast lesions

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dc.contributor.authorYılmaz, Ebru
dc.contributor.authorYılmaz, Ayhan
dc.contributor.authorAslan, Ahmet
dc.contributor.authorİnan, İbrahim
dc.contributor.authorÇalışkan Evren, Müjgan
dc.contributor.authorTekesin, Kemal
dc.date.accessioned10.07.201910:49:13
dc.date.accessioned2019-07-10T20:02:38Z
dc.date.available10.07.201910:49:13
dc.date.available2019-07-10T20:02:38Z
dc.date.issued2017
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Genel Cerrahi Ana Bilim Dalı
dc.descriptionWOS: 000417179500003
dc.descriptionPubMed ID: 29657632
dc.description.abstractBackroung: To investigate the diagnostic performance of the elastography-based strain index ratio in the differential diagnosis of malignant and benign breast lesions. Material/Methods: Seventy-nine breast masses that were classified as BI-RADS category 3, 4, and 5 on B-mode ultrasonography (US) were further prospectively evaluated by real-time sonoelastography (RTE). To obtain an optimal cut-off value of the strain ratio for differentiating between malignant and benign breast lesions, RTE findings were compared with histopathology of core needle biopsy samples or with ultrasound follow-up data of the analyzed masses. Results: Seventy-nine breast lesions [BI-RADS category 3 (n=15), BI-RADS category 4 (n=34), and BI-RADS category 5 (n=30)] were classified as malignant (n=36) or benign (n=43). The mean strain index value was 6.59 +/- 3.44 (range 0.6-14) for malignant lesions and 2.79 +/- 2.16 (range 0.6-8.7) for benign lesions, respectively (p<0.05). As regards the detection of malignant lesions, US was characterized by sensitivity and specificity of 100% (CI 95%; 88-100) and 90% (CI 95%; 76-97), respectively. When an optimal value of the strain ratio (4.25) was obtained by ROC curve analysis, the sensitivity and specificity for diagnosing malignant lesions were 86% (CI 95%; 70-95) and 76% (CI 95%; 60-87), respectively. Conclusions: RTE can play an important role in the differentiation between malignant and benign breast masses, but it should be used in conjunction with ultrasonography.
dc.identifier.citationYılmaz, E., Yılmaz, A., Aslan, A., İnan, İ., Çalışkan Evren, M. ve Tekesin, K. (2017). Real-time elastography for differentiation of breast lesions. Polish Journal of Radiology, 82, 664-669. https://dx.doi.org/10.12659/PJR.902596
dc.identifier.doi10.12659/PJR.902596
dc.identifier.endpage669
dc.identifier.issn0137-7183
dc.identifier.issn1899-0967
dc.identifier.scopusqualityQ3
dc.identifier.startpage664
dc.identifier.urihttps://dx.doi.org/10.12659/PJR.902596
dc.identifier.urihttps://hdl.handle.net/20.500.12511/3696
dc.identifier.volume82
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherInternational Scientific Information Inc.
dc.relation.ispartofPolish Journal of Radiologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectBreast Diseases
dc.subjectBreast Neoplasms
dc.subjectElasticity Imaging Techniques
dc.subjectUltrasonography, Mammary
dc.titleReal-time elastography for differentiation of breast lesions
dc.typeArticle

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