Radiological changes in the thymus in patients who have had covid-19 and in vaccinated persons who have not had covid-19: a ct study

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dc.contributor.authorTuğtağ Demir, Berin
dc.contributor.authorMetin Söğütlügil, Melike Ruşen
dc.date.accessioned2025-06-10T11:13:29Z
dc.date.available2025-06-10T11:13:29Z
dc.date.issued2024
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Radyoloji Ana Bilim Dalı
dc.description.abstractBackground: There are very few and limited studies on the role of the thymus in COVID-19 infection. It is known that thymus morphology changes in individuals vaccinated against COVID-19 although they do not have active infection. Objective: Our study aims to evaluate these differences in detail. Methods: This research was conducted in a total of 141 people, 75 women and 66 men. The research consisted of three groups: unvaccinated persons who have had the disease (n = 49), vaccinated persons who have not had the disease (n = 37), and unvaccinated persons who have not had the disease (control group, n = 55). In the study, the thymus volume, structure, and fat content were investigated and the differences between groups were evaluated. Results: Thymus volume was greatest (0.43 ± 0.11) in the vaccinated group that had not had the disease and smallest (0.15 ± 0.07) in the unvaccinated group that had had the disease, and a significant difference was found between the groups. Thymus steatosis was seen mostly in the unvaccinated group that had had the disease (72%; p = 0.04). The diffuse nodular pattern was only present in the diseased group. Conclusion: This research is the first study in the literature to date on the effect of COVID-19 and vaccines on the thymus. In addition to the acute consequences of the virus, the possibility of negative symptoms after COVID-19 should also be kept in mind, especially in unvaccinated people. Further studies are needed to confirm the results reported herein.
dc.identifier.citationTuğtağ Demir, B., Metin Söğütlügil, M. R. ve Çankal, F. (2024). Radiological changes in the thymus in patients who have had covid-19 and in vaccinated persons who have not had covid-19: a ct study. Radiologie, 64(1), 139-144. http://dx.doi.org/10.1007/s00117-024-01363-4
dc.identifier.doi10.1007/s00117-024-01363-4
dc.identifier.endpage144
dc.identifier.issn2731-7048
dc.identifier.issn2731-7056
dc.identifier.issue1
dc.identifier.pmid39259290
dc.identifier.scopus2-s2.0-85203554443
dc.identifier.scopusqualityQ4
dc.identifier.startpage139
dc.identifier.urihttp://dx.doi.org/10.1007/s00117-024-01363-4
dc.identifier.urihttps://hdl.handle.net/20.500.12511/12937
dc.identifier.volume64
dc.identifier.wosWOS:001309999900001
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorMetin Söğütlügil, Melike Ruşen
dc.institutionauthorid0000-0002-2341-4850
dc.language.isoen
dc.relation.ispartofRadiologie
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectComputerized Tomography
dc.subjectCOVID-19
dc.subjectMorphology
dc.subjectThymus
dc.subjectVaccination
dc.titleRadiological changes in the thymus in patients who have had covid-19 and in vaccinated persons who have not had covid-19: a ct study
dc.title.alternativeMorphologische veränderungen im thymus bei covid-19-patienten und geimpften: ct-studie
dc.typeArticle

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