Effect of HRT on serum lipid, apolipoprotein ai, apolipoprotein B, and lipoprotein (a) in postmenopausalwomen: Added benefits of dietary and exercise improvement

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dc.authorid0000-0002-8676-8314
dc.contributor.authorErgenekon, Pelin
dc.date.accessioned10.07.201910:49:13
dc.date.accessioned2019-07-10T19:35:54Z
dc.date.available10.07.201910:49:14
dc.date.available2019-07-10T19:35:54Z
dc.date.issued2018
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Kadın Hastalıkları ve Doğum Ana Bilim Dalı
dc.description.abstractObjective: In this quasi-experimental study, we aimed to measure the effect of hormone replacement therapy (HRT) on serum lipid, apolipoprotein AI, apolipoprotein B, and lipoprotein (a). The study had three objectives: to replicate previous studies' findings on the effect of HRT on lipid and lipoprotein profiles; to integrate possible effects of dietary and exercise improvements (considered as independent predictors), covariates, and interaction variables; and to report effect sizes capable of estimating the impact of HRT on each outcome variable of the study. Material and Methods: The effect of HRT on serum lipid, apolipoprotein AI, apolipoprotein B, and lipoprotein (a) was determined in a case group of 86 postmenopausal women compared with that in a control group of 97 age-matched women who were not receiving HRT and who were not menopausal. Results: HRT had the expected salutary effect on all measured variables, except for apolipoprotein AI. The largest effect size was observed for high-density lipoprotein cholesterol, suggesting the need for replication and if necessary, further investigation of why HRT might be particularly beneficial for highdensity lipoprotein cholesterol levels of postmenopausal women. Conclusion: Finally, the study found neither an independent nor interactive effect of diet or exercise on the effect of HRT.
dc.identifier.citationErgenekon, P. (2018). Effect of HRT on serum lipid, apolipoprotein ai, apolipoprotein B, and lipoprotein (a) in postmenopausalwomen: Added benefits of dietary and exercise improvement. Türkiye Klinikleri Jinekoloji Obstetrik, 28(4), 146-156. https://dx.doi.org/10.5336/jcog.2018-61286
dc.identifier.doi10.5336/jcog.2018-61286
dc.identifier.endpage156
dc.identifier.issn1300-0306
dc.identifier.issue4
dc.identifier.scopusqualityQ4
dc.identifier.startpage146
dc.identifier.urihttps://hdl.handle.net/20.500.12511/988
dc.identifier.urihttps://dx.doi.org/10.5336/jcog.2018-61286
dc.identifier.volume28
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherOrtadoğu Reklam Tanıtım Yayıncılık Turizm Eğitim İnşaat Sanayi ve Ticaret A.Ş.
dc.relation.ispartofTürkiye Klinikleri Jinekoloji Obstetriken_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectApolipoprotein
dc.subjectHormone Replacement Therapy
dc.subjectLipids
dc.subjectLipoprotein
dc.subjectPostmenopausal
dc.titleEffect of HRT on serum lipid, apolipoprotein ai, apolipoprotein B, and lipoprotein (a) in postmenopausalwomen: Added benefits of dietary and exercise improvement
dc.typeArticle

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