Intramedullary pancreatic adenocarcinoma metastasis: The first case in literature

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dc.authorid0000-0003-0467-7521
dc.authorid0000-0002-7597-1456
dc.authorid0000-0002-0600-5801
dc.contributor.authorTahta, Alican
dc.contributor.authorÇetinkal, Ahmet
dc.contributor.authorÇalış, Elif
dc.contributor.authorDinç, Cem
dc.date.accessioned2023-01-02T11:33:18Z
dc.date.available2023-01-02T11:33:18Z
dc.date.issued2022
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Beyin ve Sinir Cerrahisi Ana Bilim Dalı
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Tıbbi Patoloji Ana Bilim Dalı
dc.description.abstractBackground: Pancreatic cancer is a common gastrointestinal malignancy, and is often associated with a poor prognosis. Although liver is generally seen as a distant metastasis point, it has been shown that it can metastasize to any organ, especially the gastrointestinal tract, and approximately 0.3% of metastases are observed in spinal cord. Case description: We report a 36-year-old woman with a prior history of pancreatic adenocarcinoma who presented to us with a thoracic intramedullary lesion and recent onset of neurological deficits. She underwent surgery with histological confirmation of a diagnosis of metastatic adenocarcinoma. Conclusion: To our knowledge there is no prior report of pure intramedullary spinal cord metastasis from a pancreatic adenocarcinoma in the literature. We report the present patient in view of the rarity of intramedullary spinal cord metastasis and its clinical significance. Although intramedullary metastases are rare, they should be investigated in every patient with malignancy and progressive neurological deficit. While its general prognosis is poor regardless of the type of treatment, early diagnosis and treatment is important in terms of quality of life and survival.
dc.description.abstractAntecedentes El cáncer de páncreas es una neoplasia maligna gastrointestinal común y, a menudo, se asocia con un mal pronóstico. Aunque el hígado generalmente se ve como un punto de metástasis distante, se ha demostrado que puede hacer metástasis a cualquier órgano, especialmente al tracto gastrointestinal, y aproximadamente el 0,3% de las metástasis se observan en la médula espinal. Descripción del caso Presentamos una mujer de 36 años con antecedentes de adenocarcinoma de páncreas que se presentó con una lesión intramedular torácica y de reciente aparición de déficits neurológicos. Fue intervenida quirúrgicamente con confirmación histológica de diagnóstico de adenocarcinoma metastásico. Conclusión Hasta donde sabemos, no existe en la literatura ningún informe previo de metástasis intramedular pura de la médula espinal de un adenocarcinoma pancreático. Presentamos el presente paciente en vista de la rareza de la metástasis intramedular de la médula espinal y su importancia clínica. Aunque las metástasis intramedulares son raras, deben investigarse en todo paciente con neoplasia maligna y déficit neurológico progresivo. Si bien su pronóstico general es malo independientemente del tipo de tratamiento, el diagnóstico y el tratamiento precoces son importantes en términos de calidad de vida y supervivencia.
dc.identifier.citationTahta, A., Çetinkal, A., Çalış, E. ve Dinç, C. (2022). Intramedullary pancreatic adenocarcinoma metastasis: The first case in literature. Neurocirugia, 33(6), 334-339. https://doi.org/10.1016/j.neucir.2021.03.005
dc.identifier.doi10.1016/j.neucir.2021.03.005
dc.identifier.endpage339
dc.identifier.issn1130-1473
dc.identifier.issue6
dc.identifier.pmid33994284
dc.identifier.scopus2-s2.0-85105779820
dc.identifier.scopusqualityQ3
dc.identifier.startpage334
dc.identifier.urihttps://doi.org/10.1016/j.neucir.2021.03.005
dc.identifier.urihttps://hdl.handle.net/20.500.12511/10225
dc.identifier.volume33
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorTahta, Alican
dc.institutionauthorÇetinkal, Ahmet
dc.institutionauthorÇalış, Elif
dc.institutionauthorDinç, Cem
dc.language.isoen
dc.publisherNeurocirugia
dc.relation.ispartofNeurocirugiaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectIntramedullary
dc.subjectMetastasis
dc.subjectPancreatic Adenocarcinoma
dc.subjectSurgery
dc.titleIntramedullary pancreatic adenocarcinoma metastasis: The first case in literature
dc.title.alternativeMetástasis de adenocarcinoma de páncreas intramedular: Primer caso en la literatura
dc.typeArticle

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