Prediction of elevated left ventricular filling pressures in patients with preserved ejection fraction using longitudinal deformation indices of the left ventricle

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dc.contributor.authorHatipoğlu, Suzan
dc.contributor.authorÖzdemir, Nihal
dc.contributor.authorBabür Güler, Gamze
dc.contributor.authorBakal, Ruken Bengi
dc.contributor.authorGeçmen, Çetin
dc.contributor.authorCandan, Özkan
dc.contributor.authorDoğan, Cem
dc.contributor.authorUnkun, Tuba
dc.date.accessioned10.07.201910:49:13
dc.date.accessioned2019-07-10T19:52:24Z
dc.date.available10.07.201910:49:13
dc.date.available2019-07-10T19:52:24Z
dc.date.issued2015
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Kardiyoloji Ana Bilim Dalı
dc.descriptionWOS: 000366586000017
dc.descriptionPubMed ID: 25896356
dc.description.abstractAims Estimation of left ventricular (LV) filling pressures is a clinical challenge in patients with preserved ejection fraction (EF). In the present study, we investigated whether LV and atrial longitudinal strain and strain rate (SR) parameters derived by speckle tracking echocardiography (STE) could be used to predict invasively measured LV end-diastolic pressure (LVEDP) in this patient population. Methods and results LVEDP was measured before coronary angiography was performed in 65 patients with preserved EF (>= 50%) referred to elective cardiac catheterization; besides, patients enrolled underwent comprehensive echocardiographic examination before the procedure. In addition to conventional echocardiographic parameters used to evaluate diastolic function LV longitudinal strain and SR, as well as peak atrial longitudinal strain during LV systole, measurements were performed using STE. Only log-diastolic blood pressure, systolic SR, early diastolic SR, SR during isovolumetric relaxation (SRIVR), and mitral early diastolic flow velocity/SRIVR significantly correlated with LVEDP. When age-adjusted stepwise linear regression analysis was performed, SRIVRT values (beta = -20.682, t = -3.292; P = 0.002) and log-diastolic blood pressure levels (beta = 21.118, t = 3.784; P < 0.001) were independently correlated with LVEDP. Conclusion When compared with conventional echocardiographic parameters, other longitudinal strain, and SR indices, SRIVRT independently predicted LVEDP in conjunction with log diastolic blood pressure. We suggest that SRIVRT is a valuable parameter to evaluate diastolic function in patients with preserved EF.
dc.identifier.citationHatipoğlu, S., Özdemir, N., Babür Güler, G., Bakal, R. B., Geçmen, Ç., Candan, Ö. ... Unkun, T. (2015). Prediction of elevated left ventricular filling pressures in patients with preserved ejection fraction using longitudinal deformation indices of the left ventricle. European Heart Journal Cardiovascular Imaging, 16(10), 1154-1161. https://dx.doi.org/10.1093/ehjci/jev063
dc.identifier.doi10.1093/ehjci/jev063
dc.identifier.endpage1161
dc.identifier.issn2047-2404
dc.identifier.issn2047-2412
dc.identifier.issue10
dc.identifier.scopusqualityQ1
dc.identifier.startpage1154
dc.identifier.urihttps://dx.doi.org/10.1093/ehjci/jev063
dc.identifier.urihttps://hdl.handle.net/20.500.12511/2395
dc.identifier.volume16
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherOxford University Press
dc.relation.ispartofEuropean Heart Journal Cardiovascular Imagingen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectSpeckle Tracking Echocardiography
dc.subjectDiastolic Dysfunction
dc.subjectLeft Ventricular end Diastolic Pressure
dc.subjectLeft Ventricular Longitudinal Strain
dc.titlePrediction of elevated left ventricular filling pressures in patients with preserved ejection fraction using longitudinal deformation indices of the left ventricle
dc.typeArticle

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